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Merck
모든 사진(1)

주요 문서

MAB352

Sigma-Aldrich

Anti-Serotonin Antibody, clone YC5/45

culture supernatant, clone YC5/45, Chemicon®

동의어(들):

5-HT

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41
가격 및 재고 정보를 현재 이용할 수 없음 고객지원팀으로 연락바랍니다.

생물학적 소스

rat

Quality Level

항체 형태

culture supernatant

항체 생산 유형

primary antibodies

클론

YC5/45, monoclonal

종 반응성

mouse, human, rat, lizard, rabbit, pig

제조업체/상표

Chemicon®

기술

immunohistochemistry: suitable

동형

IgG

배송 상태

dry ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... HTR1A(3350)

특이성

Recognizes the formaldehyde conjugate of serotonin. Without paraformaldehyde treatment, it cross-reacts in liquid phase with dopamine and tryptamine in hemagglutination tests. Shows no reactivity with catecholamine-containing neurons in formaldehyde fixed preparations. MAB352 reacts with serotonin in neurons and recognizes serotonergic sites in fixed tissue sections. By cell agglutination, no cross reactivity with 5-hydroxyindolacetic acid, GABA, noradrenaline, 5-hydroxytryptophan, carnosine or melatonin.

면역원

Serotonin conjugated to BSA.

애플리케이션

Anti-Serotonin Antibody, clone YC5/45 is an antibody against Serotonin for use in IH.
Immunohistochemistry at 1:100-1:200 for formaldehyde fixed tissue.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

물리적 형태

Lyophilized Supernatant, preservative free.
Unpurified

저장 및 안정성

Lyophilized antibody can be kept at 2-8°C for up to 3 months and should be kept at -20°C for long term storage. Reconstitute with 100μL sterile DI water. Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze-thaw cycles.

분석 메모

Control
Brain tissue

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2


시험 성적서(COA)

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문서 라이브러리 방문

Basudha Basu et al.
Reproduction (Cambridge, England), 135(5), 657-669 (2008-02-29)
Serotonin is reported to be present in early embryos of many species and plays an important role in early patterning. Since it is a fluorophore, it can be directly visualized using fluorescence microscopy. Here, we use three-photon microscopy to image
Carlos Pantoja et al.
Neuron, 91(3), 587-601 (2016-07-12)
Inter-individual behavioral variation is thought to increase fitness and aid adaptation to environmental change, but the underlying mechanisms are poorly understood. We find that variation between individuals in neuromodulatory input contributes to individuality in short-term habituation of the zebrafish (Danio
Alexander Drobyshevsky et al.
Journal of neurochemistry, 132(4), 394-402 (2014-11-26)
We hypothesized that a deficiency in the descending serotonergic input to spinal cord may underlie postnatal muscle hypertonia after global antenatal hypoxic-ischemic injury in a rabbit model of cerebral palsy. Neurotransmitter content was determined by HPLC in the spinal cord
Tanimul Alam et al.
Nature communications, 7, 10388-10388 (2016-01-23)
The molecular mechanisms underlying the ability of axons to regenerate after injury remain poorly understood. Here we show that in Caenorhabditis elegans, axotomy induces ectopic expression of serotonin (5-HT) in axotomized non-serotonergic neurons via HIF-1, a hypoxia-inducible transcription factor, and
3-D imaging and illustration of mouse intestinal neurovascular complex.
Fu, YY; Peng, SJ; Lin, HY; Pasricha, PJ; Tang, SC
American Journal of Physiology: Gastrointestinal and Liver Physiology null

질문

  1. MAB352 Is this a mouse monoclonal Ab? I see Rat in the source which is unusual for me. What secondary is ideal

    1 답변
    1. This product is a rat monoclonal Antibody. An anti-rat secondary antibody would be suitable. Please see the link below to review examples of anti-rat secondary antibodies:
      https://www.sigmaaldrich.com/US/en/search/anti-rat-antibody?facet=facet_product_category%3Asecondary%20antibodies&focus=products&page=1&perpage=30&sort=relevance&term=anti-rat%20antibody&type=product

      도움이 되었습니까?

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