FCMAB196P

Milli-Mark^® Anti-CD42b-PE Antibody, clone AN51

clone AN51, Milli-Mark^®, from mouse

• 동의어(들): Platelet glycoprotein Ib alpha chain, Glycoprotein Ibalpha, GP-Ib alpha, GPIb-alpha, GPIbA, Antigen CD42b-alpha
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.44

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: PE
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: AN51, monoclonal
• 종 반응성: human
• 제조업체/상표: Milli-Mark^®
• 기술: flow cytometry: suitable
• 동형: IgG2aκ
• NCBI 수납 번호: NP_000164
• UniProt 수납 번호: P07359
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... GP1BA(2811)

설명

일반 설명

CD42b is a 145 kDa protein, which together with CD42c forma a 160 kDa heterodimer composed of an alpha-chain and a beta-chain, respectively. The subunits are linked together by a disulphide bond. CD42b and CD42c forms a non-covalent complex together with CD42a and CD42d in the platelet plasma membrane. The CD42 complex serves as a receptor for von Willebrand factor and thrombin and mediates adhesion of platelets to subendothelial matrices (exposed upon damage to the endothelium) at high shear rates. The binding sites for von Willebrand factor and thrombin lies on CD42b (de Haas, 2002). CD42 is expressed on megakarytocytes and platelets (McMichael, 1981).

특이성

Antibody recognizes Human CD42b antigen.

면역원

Mixture of human platelets and lymphocytes.

애플리케이션

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

This Milli-Mark Anti-CD42b-PE Antibody, clone AN51 is validated for use in FC for the detection of CD42b.

품질

Evaluated by flow cytometry using human lymphocytes

표적 설명

145 kDa (de Haas, 2002)

물리적 형태

Protein A purified

Purified Mouse monoclonal IgG2a conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

저장 및 안정성

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.

분석 메모

Control
Human Lymphocytes

법적 정보

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable