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Merck
모든 사진(1)

문서

ABS580

Sigma-Aldrich

Anti-FSH, β-subunit Antibody

serum, from goat

동의어(들):

Follitropin subunit beta, Follicle-stimulating hormone beta subunit, FSH-B, FSH-beta, Follitropin beta chain

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

goat

Quality Level

항체 형태

serum

항체 생산 유형

primary antibodies

클론

polyclonal

종 반응성

human, mouse

기술

ELISA: suitable
activity assay: suitable
immunohistochemistry: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... FSHB(2488)
mouse ... Fshb(14308)

일반 설명

FSH-beta is the critical subunit of FSH hormone, also called Follitropin, and several other hormones. The alpha subunits of LH, FSH, TSH and, hCG are identical, however the beta subunits vary determine the interaction with the receptors. The FSH-beta confers the biological specificity for several growth factors including Follitropin, Thyrotropin, Lutropin and Gonadotropin. FSH is involved in follicle and spermatogenesis and is secreted by the anterior pituitary gland. FSH is also expressed by testis, so FSH-beta can be found there as well during development and in adult tissues.

면역원

Linear peptide corresponding to a 13-amino acid receptor-binding sequence (LVYKDPARPNTQK) of the β-subunit of mouse FSH.

애플리케이션

Activity Assay Analysis: This antiserum was reported to neutralize FSH-induced osteoclast formation in mouse bone marrow cultures (Zhu, L.L., et al. (2012). PNAS. 109:14574-14579)
ELISA: This antiserum was reported to detect the immunogen peptide as well as full-lengh FSH by ELISA (Zhu, L.L., et al. (2012). PNAS. 109:14574-14579).
Research Category
Signaling
Research Sub Category
Signaling Neuroscience
This Anti-FSH, β-subunit Antibody is validated for use in Immunohistochemistry and Activity Assay and ELISA for the detection of FSH, β-subunit.

품질

Evaluated by Immunohistochemistry in human testis and human fallopian tube tissue.

Immunohistochemistry Analysis: A 1:1,000 dilution of this antibody detected FSH, β-subunit in human testis and human fallopian tube tissue.

표적 설명

15 kDa (calculated); 19 kDa (glycosylated).

물리적 형태

Goat polyclonal serum without preservatives.
Unpurified

저장 및 안정성

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

기타 정보

Concentration: Please refer to lot specific datasheet.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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