ABE483
Anti-TFAM Antibody
serum, from rabbit
동의어(들):
Transcription factor A, mitochondrial, mtTFA, Testis-specific high mobility group protein, TS-HMG
로그인조직 및 계약 가격 보기
크기 선택
100 μL
₩540,386
₩540,386
예상 입고일2025년 5월 23일세부사항
모든 사진(2)
크기 선택
보기 변경
100 μL
₩540,386
About This Item
UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41
₩540,386
예상 입고일2025년 5월 23일세부사항
추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
serum
항체 생산 유형
primary antibodies
클론
polyclonal
종 반응성
human, mouse, rat
기술
immunoprecipitation (IP): suitable
western blot: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... TFAM(7019)
mouse ... Tfam(21780)
일반 설명
TFAM, also called mtTFA, is a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development.
면역원
His-tagged recombinant protein corresponding to mouse mtTFA.
애플리케이션
Detect TFAM using this rabbit polyclonal antibody, Anti-TFAM Antibody validated for use in western blotting & IP.
Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated TFAM in C2C12 cell lysate (Prof. B Kaufman, University of Pennsylvania.).
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Transcription Factors
품질
Evaluated by Western Blotting in C2C12 cell lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected TFAM in 10 µg of C2C12 cell lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected TFAM in 10 µg of C2C12 cell lysate.
표적 설명
~27 kDa observed
물리적 형태
Rabbit polyclonal serum containing 0.05% sodium azide.
Unpurified
저장 및 안정성
Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
적합한 제품을 찾을 수 없으신가요?
당사의 제품 선택기 도구.을(를) 시도해 보세요.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Jong-Hyuk Lee et al.
Experimental & molecular medicine, 54(12), 2135-2147 (2022-12-07)
PARPs play fundamental roles in multiple DNA damage recognition and repair pathways. Persistent nuclear PARP activation causes cellular NAD+ depletion and exacerbates cellular aging. However, very little is known about mitochondrial PARP (mtPARP) and poly ADP-ribosylation (PARylation). The existence of
Wenci Weng et al.
Experimental and therapeutic medicine, 23(3), 239-239 (2022-03-01)
Type 1 diabetes (T1D) is characterized by dysregulated blood glucose and liver metabolism. In previous studies, niclosamide ethanolamine salt (NEN) and artemether (Art) displayed significant hypoglycemic effects. However, their combined therapeutic effects on the liver in T1D have remained elusive.
Krishna Prahlad Maremanda et al.
Toxicology and applied pharmacology, 385, 114788-114788 (2019-11-05)
Cigarette smoke (CS)-induced lung inflammation and Chronic Obstructive Pulmonary disease (COPD) involves mitochondrial dysfunction. Mesenchymal stem cells (MSC) and MSC-derived exosomes (EXO) are reported to show therapeutic effects in many animal models of inflammation and injury. In the present study
Nicole DeFoor et al.
Scientific reports, 13(1), 15339-15339 (2023-09-16)
SARS-CoV-2 causes the severe respiratory disease COVID-19. Remdesivir (RDV) was the first fast-tracked FDA approved treatment drug for COVID-19. RDV acts as an antiviral ribonucleoside (adenosine) analogue that becomes active once it accumulates intracellularly. It then diffuses into the host
Sylvia Torres-Odio et al.
Journal of immunology (Baltimore, Md. : 1950), 206(8), 1890-1900 (2021-03-19)
Caseinolytic mitochondrial matrix peptidase proteolytic subunit (CLPP) is a serine protease that degrades damaged or misfolded mitochondrial proteins. CLPP-null mice exhibit growth retardation, deafness, and sterility, resembling human Perrault syndrome, but also display immune system alterations. However, the molecular mechanisms
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.
