ABC521

Anti-Rab21 Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): Ras-related protein Rab-21
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: mouse, human, rat
• 기술: western blot: suitable
• NCBI 수납 번호: NP_055814
• UniProt 수납 번호: Q9UL25
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... RAB21(23011)

설명

일반 설명

RAB21 is a member of the small GTPase superfamily that is critically important in the recycling of integrin protein receptor complexes and their internalization. Thus, RAB21 is important in cell adhesion and migration of cells, as well as the proper completing of cytokinesis which requires particular care with adherent cells to coordinate the release and recycling of integrin and their release from the ECM matrix during cytokinesis. RAB21 is primarily a cytoplasmic or cytoplasmic organelle localized protein and its precise location will vary with cell cycle and cell division phases. RAB21 is widely expressed particularly in cells in the gut and capillaries where cell division and cell morphological changes are common.

면역원

GST-tagged recombinant protein corresponding to Mouse Rab21.

애플리케이션

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

This Anti-Rab21 Antibody is validated for use in Western Blotting for the detection of Rab21.

Western Blot Analysis: A 1:1000 dilution of a representative lot of this antibody detected Rab21 in A431, C2C12, HEK293, HeLa, HepG2, Jurkat, L6, Mouse brain, NIH/3T3, PC12, PC3, and RAW264.7 cell lysates. This antibody did not detect Rab21 in Human placenta or Huvec cell lysates.

Western Blot Analysis: A representative lot of this antibody detected Rab21 in melanocyte membrane compartment lysate (Ohbayashi et al., (2012) Mol Biol Cell. 23(4):669-678).

품질

Evaluated by Western Blotting in PC12 cell lysate.

Western Blotting Analysis: A 1:1000 dilution of this antibody detected Rab21 in 10 µg of PC12 cell lysate.

표적 설명

~24 kDa observed.
Uncharacterized bands may be obeserved in some lysates.

물리적 형태

Antigen Affinity Purified

Purified rabbit Polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

기타 정보

Concentration: Please refer to lot specific datasheet.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable