Mitochondrial carrier homolog 2 (MTCH2) may play a key role in the mitochondrial apoptosis pathway and may induce mitochondrial depolarization. MTCH2 is suggested to catalyze the exchange of substrates across the inner mitochondrial membrane in response to apoptotic signals. Additionally, it is suggested to be targeted by Bid, a pro-apoptotic Bcl-2 family member. The Bcl-2 family of proteins incorporates a number of critical regulators of apoptosis that can be divided into two classes: inhibitors of apoptosis and promoters of cell death. Apoptosis plays a major role in tissue homeostasis, normal organism development, and removal of damaged cells. The disruption of this process has been linked to a variety of diseases such as cancer.
면역원
KLH-conjugated linear peptide corresponding to human MTCH2.
애플리케이션
Anti-MTCH2 Antibody is a highly specific rabbit polyclonal antibody, that targets Mitochondrial carrier homolog 2 & has been tested in western blotting, IHC & Immunofluorescence.
Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected MTCH2 in mouse kidney tissue.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected MTCH2 in mouse kidney cells.
품질
Evaluated by Western Blotting in HEK293 cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected MTCH2 in 15 µg of HEK293 cell lysate.
표적 설명
~34 kDa observed.
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.