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Merck
모든 사진(1)

주요 문서

AB3538P

Sigma-Aldrich

Anti-Monocarboxylate Transporter 1 Antibody

Chemicon®, from rabbit

동의어(들):

MCT1

로그인조직 및 계약 가격 보기

크기 선택

50 μG
₩831,793

₩831,793


예상 입고일2025년 5월 15일세부사항


벌크 견적 요청

크기 선택

보기 변경
50 μG
₩831,793

About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

₩831,793


예상 입고일2025년 5월 15일세부사항


벌크 견적 요청

생물학적 소스

rabbit

Quality Level

항체 형태

affinity purified immunoglobulin

항체 생산 유형

primary antibodies

클론

polyclonal

정제법

affinity chromatography

종 반응성

human

제조업체/상표

Chemicon®

기술

ELISA: suitable
western blot: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... SLC16A1(6566)

특이성

Recognizes human Monocarboxylate Transporter 1 (MCT1). The immunogen shows no significant sequence homology with MCT2-8.

면역원

A 15 amino acid peptide sequence near the C-terminus of human MCT1 (Gerhart et al. 1997; Knott et al. 1999; Takanaga et al. 1995; Carpenter et al. 1996; Koehler-Stec et al. 1998; Yoon et al. 1999; Halestrap & Price 1999).

애플리케이션

Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
This Anti-Monocarboxylate Transporter 1 Antibody is validated for use in ELISA, WB for the detection of Monocarboxylate Transporter 1.
Western blot: 1-5 μg/mL using ECL.
ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide per well.
Optimal working dilutions must be determined by the end user.

물리적 형태

Affinity purified immunoglobulin. Liquid in PBS containing 0.1% BSA.

저장 및 안정성

Maintain at -20°C in undiluted aliquots for up to 6 months from date of receipt. Avoid repeated freeze/thaw cycles.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Chun-Kai Huang et al.
Nature communications, 8, 14706-14706 (2017-03-11)
Adipocytes are the most abundant stromal partners in breast tissue. However, the crosstalk between breast cancer cells and adipocytes has been given less attention compared to cancer-associated fibroblasts. Here we find, through systematic screening, that primary mammary gland-derived adipocytes (MGDAs)
Expression of monocarboxylate transporters 1, 2, and 4 in human tumours and their association with CD147 and CD44.
Pinheiro, C; Reis, RM; Ricardo, S; Longatto-Filho, A; Schmitt, F; Baltazar, F
Journal of Biomedicine and Biotechnology null
Julieta Afonso et al.
Cell cycle (Georgetown, Tex.), 15(3), 368-380 (2015-12-05)
Monocarboxylate transporters (MCTs) are vital for intracellular pH homeostasis by extruding lactate from highly glycolytic cells. These molecules are key players of the metabolic reprogramming of cancer cells, and evidence indicates a potential contribution in urothelial bladder cancer (UBC) aggressiveness
Vincent F Van Hée et al.
Oncotarget, 8(15), 24415-24428 (2017-01-21)
Cancers develop metabolic strategies to cope with their microenvironment often characterized by hypoxia, limited nutrient bioavailability and exposure to anticancer treatments. Among these strategies, the metabolic symbiosis based on the exchange of lactate between hypoxic/glycolytic cancer cells that convert glucose
S-Nitrosation of monocarboxylate transporter 1: inhibition of pyruvate-fueled respiration and proliferation of breast cancer cells.
Diers, AR; Broniowska, KA; Chang, CF; Hill, RB; Hogg, N
Free radical biology & medicine null

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