Reacts with histone H2B in human nuclear fractions. No cross-reactivity with other histones, H1, H2A, H3 or H4. Binding of histones from other species has not been tested, but it is likely as the amino acid sequence of histone H2B has been found to be identical in all species examined.
면역원
Synthetic peptide
애플리케이션
Detect Histone H2B also known as Histone H2B with Anti-Histone H2B Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in WB & IHC.
Research Category Epigenetics & Nuclear Function
Research Sub Category Histones
Western blot
Immunohistochemistry on paraformaldehyde treated sections.
Optimal working dilutions must be determined by end user.
결합
Replaces: MABE15
물리적 형태
Rabbit antiserum. Liquid. Contains no preservative.
저장 및 안정성
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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The packaging of DNA into nucleosomes imposes obstacles on gene transcription, and histone-modifying and nucleosome-remodeling complexes work in concert to alleviate these obstacles so as to facilitate transcription. Emerging evidence shows that chromatin-associated poly(ADP-ribose) polymerase 1 (PARP-1) and its enzymatic
Neurobiology of aging, 36(10), 2850-2860 (2015-08-11)
The progressive loss of neurons causes neurodegenerative diseases. Because the accumulation of DNA breaks results in neuronal apoptosis, the lack of a variety of DNA damage repair-related proteins contributes to neurodegeneration. The ubiquitin ligase RNF8 plays an important role in
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