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Merck
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주요 문서

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579002

Sigma-Aldrich

(Z)-4-Hydroxytamoxifen

≥99% (HPLC), solid, estrogen receptor modulator, Calbiochem

동의어(들):

Tamoxifen, 4-Hydroxy-, (Z)-, (Z)-4-Hydroxytamoxifen, 4-OH-TAM, Estrogen Receptor Signaling Regulator II

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About This Item

실험식(Hill 표기법):
C26H29NO2
CAS Number:
68047-06-3
Molecular Weight:
387.51
MDL number:
MFCD00278780
UNSPSC 코드:
12352200
NACRES:
NA.77

제품명

Tamoxifen, 4-Hydroxy-, (Z)-, A cell-permeable, active metabolite of Tamoxifen that acts as a potent inhibitor of PKC. It is more potent than the parent compound and inhibits PKC by modifying its catalytic domain.

Quality Level

200

분석

≥99% (HPLC)

양식

solid

제조업체/상표

Calbiochem®

저장 조건

OK to freeze

색상

white

solubility

methanol: 10 mg/mL
ethanol: 20 mg/mL (heating may be required)

배송 상태

ambient

저장 온도

2-8°C

InChI

1S/C26H29NO2/c1-4-25(20-10-14-23(28)15-11-20)26(21-8-6-5-7-9-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3/b26-25-

InChI key

DODQJNMQWMSYGS-QPLCGJKRSA-N

일반 설명

A cell-permeable, active metabolite of Tamoxifen (Cat. No. 579000) that acts as a potent inhibitor of PKC. It is more potent than the parent compound and inhibits PKC by modifying its catalytic domain. Also available as a 10 mM solution in EtOH (Cat. No. 508225).

생화학적/생리학적 작용

Cell permeable: yes
Primary Target
PKC
Product does not compete with ATP.
Reversible: no

경고

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

기타 정보

Gundimeda, U., et al. 1996. J. Biol. Chem. 271, 13504.
Ye, Q. and Bodell, W.J. 1996. Carcinogenesis 17, 1747.
Laser, R., et al. 1985. Eur. J. Cancer Clin. Oncol. 21, 985.
Jordan, V.C., et al. 1978. J. Toxicol. Environ. Health 4, 364.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

픽토그램

Health hazardExclamation markEnvironment
GHS08,GHS07,GHS09

신호어

Danger

유해 및 위험 성명서

H302,H350,H360FD,H410

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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