539508

PP2A₁, Bovine Kidney

• 동의어(들): Protein Phosphatase 2A₁
• 효소 위원회 번호: 3.1.3.16 (BRENDA, IUBMB)
• UNSPSC 코드: 12352202

속성

• 분석: ≥90% (SDS-PAGE)
• Quality Level: 100
• 양식: liquid
• 특이 활성도: ≥750 units/mg protein
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 배송 상태: wet ice
• 저장 온도: −20°C

설명

일반 설명

Native, PP2A₁ from bovine kidney. A divalent cation-independent protein serine/threonine phosphatase involved in the control of numerous cellular processes. Has a catalytic subunit of 36 kDa, a subunit of 55 kDa, and a regulatory subunit of 60 kDa. Reported to associate with microtubules and to bind to purified tubulin polymerized by TAXOL^® Drug.

포장

Please refer to vial label for lot-specific concentration.

경고

Toxicity: Standard Handling (A)

단위 정의

One unit is defined as the amount of enzyme that will release 1.0 nmol of [³²P]P_i from ³²P-labeled phosphorylase per min at 30°C, pH 7.0.

물리적 형태

In 50 mM Tris-HCl, 14 mM β-ME, 1 mM benzamidine, 1 mM EDTA, 100 µM PMSF, 50% glycerol, pH 7.0.

재구성

Following initial thaw, aliquot and freeze (-20°C).

기타 정보

Hiraga, A. and Tamura, S. 2000. Biochem. J.346, 433.
Ferrigno, P., et al. 1993. Mol. Biol. Cell. 4, 669.
Guo, H. and Damuni, Z. 1993. Proc. Natl. Acad. Sci. USA90, 2500.
Hendrix, P., et al. 1993. J. Biol. Chem.268, 15267.
Amick, G.D., et al. 1992. Biochem. J. 287, 1019.
Cohen, P., et al. 1990. Trends Biochem. Sci.15, 98.
Damuni, Z., et al. 1989. J. Biol. Chem.264, 6412.1

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Taxol is a registered trademark of Bristol-Myers Squibb Co.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable