5.05816

Xanomeline Oxalate

• 동의어(들): Xanomeline Oxalate, 3-(hexyloxy)-4-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)-1,2,5-thiadiazole, Muscarinic Acetylcholine Receptor (mAChR) Agonist, Xanomeline
• 실험식(Hill 표기법): C₁₄H₂₃N₃OS · xC₂H₂O₄
• CAS Number: 141064-23-5
• Molecular Weight: 281.42 (free base basis)
• MDL number: MFCD12828778
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 분석: ≥99% (HPLC)
• Quality Level: 100
• 양식: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; protect from light
• 색상: off-white
• solubility: DMSO: 10 mM; ethanol: 25 mM
• 저장 온도: 2-8°C
• SMILES string: [s]1nc(c(n1)C2=CCCN(C2)C)OCCCCCC.OC(=O)C(=O)O
• InChI: 1S/C14H23N3OS.C2H2O4/c1-3-4-5-6-10-18-14-13(15-19-16-14)12-8-7-9-17(2)11-12;3-1(4)2(5)6/h8H,3-7,9-11H2,1-2H3;(H,3,4)(H,5,6)
• InChI key: ZJOUESNWCLASJP-UHFFFAOYSA-N

설명

일반 설명

An agonist selective for muscarinic acetylcholine receptor (mAChR) subtype M1 (EC₅₀ = 0.3, 5, 42, 52 and 92.5 nM at M₁, M₃, M₅, M₄ and M₂ receptors respectively). An antipsychotic agent. Used in improving cognitive deficits and behavioral disturbances in Alzheimer′s disease and schizophrenia.

경고

Toxicity: Standard Handling (A)

기타 정보

Wang, D., et al., 2011. Biochem. Biophys. Res. Commun.410, 229.
Si, W., et al., 2010. Neurosci. Lett.473, 115.
Stanhope, et al., 2001. J. Exp. Pharmacol. Ther.299, 782.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301
• 예방조치 성명서: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable