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Merck
모든 사진(1)

주요 문서

454582

Sigma-Aldrich

Anti-NMDAR 2B (984-1104) Rabbit pAb

lyophilized, Calbiochem®

동의어(들):

Anti-N-Methyl-D-Aspartate Receptor 2B-Subunit

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.43
가격 및 재고 정보를 현재 이용할 수 없음

생물학적 소스

rabbit

Quality Level

항체 형태

purified antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

lyophilized

미포함

preservative

종 반응성

rat, fish, mouse, human

제조업체/상표

Calbiochem®

저장 조건

OK to freeze

동형

IgG

배송 상태

ambient

저장 온도

−20°C

타겟 번역 후 변형

unmodified

일반 설명

Immunoaffinty purified rabbit polyclonal antibody. Recognizes the ~180 kDa NMDAR2B subunit of the NMDA receptor.
Recognizes the ~180 kDa NMDA receptor NR2B subunit.
This Anti-NMDAR 2B (984-1104) Rabbit pAb is validated for use in Immunoblotting, Immunohistochemistry, Immunoprecipitation for the detection of NMDAR 2B (984-1104).

면역원

Rat Brain
a recombinant fusion protein consisting of amino acids 984-1104 of rat brain NMDAR 2B-subunit

애플리케이션

Immunoblotting (1:1000)

Immunohistochemistry (1:1000-1:2000)

Immunoprecipitation (see comments)

경고

Toxicity: Standard Handling (A)

물리적 형태

Lyophilized from 5 mM ammonium bicarbonate.

재구성

Reconstitute in 50 µl PBS. Following reconstitution, aliquot and freeze (-20°C). Avoid freeze thaw cycles of reconstituted solution.

기타 정보

Does not cross-react with NMDAR2A or NMDAR2C. Please refer to the certificate of analysis for lot-specific immunoprecipitation volume. Variables associated with assay conditions will dictate the proper working dilution.
Wang, Y.H., et al. 1995. J. Neurochem.65, 176.
Petralia, R.S., et al. 1994. J. Neurosci.14, 6102.
Ishii, T., et al. 1993. J. Biol. Chem.268, 2836.
Monyer, H., et al. 1992. Nature256, 1217.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Ainhoa Plaza-Zabala et al.
Neuroscience letters, 557 Pt B, 101-106 (2013-11-23)
Hypocretin peptides are critical for the effects of cocaine on excitatory synaptic strength in the ventral tegmental area (VTA). However, little is known about their role in cocaine-induced synaptic plasticity in the nucleus accumbens (NAc). First, we tested whether hypocretin-1
Carrie R Ferrario et al.
PloS one, 7(8), e40898-e40898 (2012-08-08)
We previously showed that the time-dependent intensification ("incubation") of cue-induced cocaine seeking after withdrawal from extended-access cocaine self-administration is accompanied by accumulation of Ca(2+)-permeable AMPA receptors (CP-AMPARs) in the rat nucleus accumbens (NAc). These results suggest an enduring change in
Leonardo Santana Novaes et al.
Translational psychiatry, 11(1), 18-18 (2021-01-09)
The persistence of anxiety and the deficit of fear memory extinction are both phenomena related to the symptoms of a trauma-related disorder, such as post-traumatic stress disorder (PTSD). Recently we have shown that single acute restraint stress (2 h) in rats
Daniela Bonini et al.
Neural plasticity, 2016, 7267865-7267865 (2016-03-12)
Clinical studies on patients with stress-related neuropsychiatric disorders reported functional and morphological changes in brain areas where glutamatergic transmission is predominant, including frontal and prefrontal areas. In line with this evidence, several preclinical works suggest that glutamate receptors are targets
Carrie R Ferrario et al.
Neuroscience letters, 490(3), 180-184 (2010-12-25)
We characterized the distribution of AMPA receptor (AMPAR) subunits and the transmembrane AMPA receptor regulatory proteins (TARPs) γ-2 and γ-4 in adult rat nucleus accumbens (NAc) using a method that separates plasma membranes into synaptic membrane-enriched and extrasynaptic membrane-enriched fractions.

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