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Merck
모든 사진(1)

문서

420355

Sigma-Aldrich

Isoprenaline hydrochloride

≥99% (TLC), solid, β-adrenoceptor agonist, Calbiochem

동의어(들):

Isoproterenol, Hydrochloride

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C11H17NO3 · xHCl
CAS Number:
51-30-9
Molecular Weight:
211.26 (free base basis)
MDL number:
MFCD00012603
UNSPSC 코드:
12352200
NACRES:
NA.77

product name

Isoproterenol, Hydrochloride, Phenethylamine derivative.

Quality Level

100

분석

≥99% (TLC)

형태

solid

제조업체/상표

Calbiochem®

저장 조건

OK to freeze
protect from light

색상

white to off-white
 white

solubility

ethanol: soluble
water: soluble

배송 상태

ambient

저장 온도

10-30°C

InChI

1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H

InChI key

IROWCYIEJAOFOW-UHFFFAOYSA-N

일반 설명

Phenethylamine derivative. Selective β-adrenergic agonist that increases cytosolic cAMP. Promotes glycogen breakdown and causes bronchodilation. Increases Cl- diffusion and potential difference in rabbit trachea cells through nitric oxide generation.
Phenethylamine derivative. Selective β-adrenergic agonist that stimulates adenylate cyclase activity. Promotes glycogen breakdown and causes bronchodilation. Increases Cl– diffusion and potential difference in rabbit trachea cells through nitric oxide generation. Reported to activate MAP Kinase (ERK) by a Rap1 and B-Raf dependent process.

생화학적/생리학적 작용

Cell permeable: no
Primary Target
β-adrenergic agonist
Product does not compete with ATP.
Reversible: no

경고

Toxicity: Irritant (B)

재구성

Unstable in solution; reconstitute just prior to use.

기타 정보

Schmitt, J.M., and Stork, P.J. 2000. J. Biol. Chem.275, 25342.
Carmena, M.J., et al. 1997. Prostate 33, 46.
Takemura, H., et al. 1995. J. Pharmacol. Exp. Ther. 274, 584.
Kishimoto, I., et al. 1994. J. Biol. Chem.269, 28300.
Macaulay, S.L., et al. 1994. Mol. Cell Biochem.141, 27.
Yashiro, K., et al. 1994. J. Biochem.115, 1040.
Ladenheim, R.G., et al. 1993. J. Neurochem.60, 260.
von Zastrow, M., et al. 1993. J. Biol. Chem.268, 763.
Mokhtari, A., et al. 1985. J. Cyclic Nucleotide Protein Phosphorylation Res.10, 213.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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