420311

Kanamycin Sulfate, Streptomyces kanamyceticus

An aminoglycoside antibiotic effective against Gram-positive and Gram-negative organisms.

• 동의어(들): Kanamycin Sulfate, Streptomyces kanamyceticus, Kamycin
• 실험식(Hill 표기법): C₁₈H₃₆N₄O₁₁ · xH₂SO₄
• CAS Number: 25389-94-0
• Molecular Weight: 484.50 (free base basis)
• UNSPSC 코드: 51281654

속성

• Quality Level: 100
• 양식: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 색상: white to off-white
• solubility: water: 10 mg/mL
• 배송 상태: ambient
• 저장 온도: 10-30°C
• InChI: 1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;/m1./s1
• InChI key: OOYGSFOGFJDDHP-KMCOLRRFSA-N

설명

일반 설명

Contains more than 98% kanamycin A. An aminoglycoside antibiotic affective against gram-positive and gram-negative organisms. Inhibitor of protein biosynthesis that acts on the 70S ribosome, causing misreading of the genetic code. May cause renal damage and ototoxicity.

Potency: ≥750 µg/mg

생화학적/생리학적 작용

Primary Target
protein biosynthesis

재구성

Following reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

기타 정보

Lech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., eds.) John Wiley & Sons, New York.
Kahn, R.W., et al. 1993. Proc. Natl. Acad. Sci. USA90, 9295.
Cardon, G.H., et al. 1993. Plant J.3, 773.
Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties1, 690.
Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother.6, 516.
Umezawa, S., et al. 1968. J. Antibiot.21, 367.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H360D
• 예방조치 성명서: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2