382180
Histone Deacetylase 6, GST-Fusion, Human Recombinant, S. frugiperda
Histone Deacetylase 6, GST-Fusion, Human Recombinant, S. frugiperda, is a full-length HDAC6 fused to GST at the N-terminus. Useful in the study of HDAC6 regulation and for inhibitor screening.
동의어(들):
HDAC6, Human, Recombinant
로그인조직 및 계약 가격 보기
크기 선택
50 μG
₩1,006,373
₩1,006,373
예상 입고일2025년 4월 25일세부사항
모든 사진(1)
크기 선택
보기 변경
50 μG
₩1,006,373
About This Item
UNSPSC 코드:
12352202
NACRES:
NA.54
₩1,006,373
예상 입고일2025년 4월 25일세부사항
추천 제품
재조합
expressed in insect cells (S. frugiperda)
Quality Level
분석
≥80% (SDS-PAGE)
양식
liquid
특이 활성도
≥50 units/μg protein
제조업체/상표
Calbiochem®
저장 조건
OK to freeze
avoid repeated freeze/thaw cycles
배송 상태
wet ice
저장 온도
−70°C
일반 설명
Full length, recombinant, human histone deacetylase 6 (HDAC6) fused to GST at the N-terminus and expressed in S. frugiperda insect cells using a baculovirus expression system. Actively maintained in the cytoplasm, HDAC6 is uniquely dependent on its ubiquitin-binding domain and functions at the nexus between two cellular signaling systems, involving protein acetylation and ubiquitination. The active deacetylase is useful in the study of HDAC6 regulation and for inhibitor screening.
포장
Please refer to vial label for lot-specific concentration.
경고
Toxicity: Standard Handling (A)
단위 정의
One unit is defined as the amount of enyme that is required to deacetylate 1 pmol fluorescent HDAC peptide substrate per min at 30°C.
물리적 형태
40 mM Tris-HCl pH8.0, 110mM NaCl, 2.2 mM KCl, 0.04% Tween 20, 3mM DTT, and 20% glycerol.
재구성
Following initial thaw, aliquot and freeze (-70°C).
기타 정보
Pandey, U.B., et al. 2007. Nature447, 859.
Hubbert, C., et al. 2002. Nature417, 455.
Hubbert, C., et al. 2002. Nature417, 455.
법적 정보
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Jin Kyun Park et al.
Arthritis research & therapy, 23(1), 177-177 (2021-07-07)
To investigate the effects of inhibiting histone deacetylase (HDAC) 6 on inflammatory responses and tissue-destructive functions of fibroblast-like synoviocytes (FLS) in rheumatoid arthritis (RA). FLS from RA patients were activated with interleukin (IL)-1β in the presence of increasing concentrations of
Nina Ha et al.
British journal of pharmacology, 177(22), 5096-5113 (2021-01-19)
Charcot-Marie-Tooth (CMT) disease is the most common hereditary peripheral neuropathy. CMT type 1A (CMT1A) accounts for approximately 50% of CMT patients and is linked to PMP22 gene duplication. Histone deacetylase-6 (HDAC6) has pleiotropic effects, such as regulating lipid homeostasis and
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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