370660

Guanosine 3′,5′-cyclic Monophosphate, N²,2′-O-Dibutyryl-, Sodium Salt

Cell-permeable cGMP analog that preferentially activates protein kinase G.

• 동의어(들): Guanosine 3′,5′-cyclic Monophosphate, N²,2′-O-Dibutyryl-, Sodium Salt, Dibutyryl-cGMP, Na
• 실험식(Hill 표기법): C₁₈H₂₃N₅O₉P · Na
• CAS Number: 51116-00-8
• Molecular Weight: 507.37
• MDL number: MFCD00038422
• UNSPSC 코드: 41106305
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 양식: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; desiccated (hygroscopic)
• 색상: white
• solubility: ethanol: soluble; water: soluble
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: [Na+].[P]1(=O)(O[C@@H]2[C@H](O[C@H]([C@@H]2OC(=O)CCC)[n]3c4nc(nc(c4nc3)O)NC(=O)CCC)CO1)[O-]
• InChI: 1S/C18H24N5O9P.Na/c1-3-5-10(24)20-18-21-15-12(16(26)22-18)19-8-23(15)17-14(31-11(25)6-4-2)13-9(30-17)7-29-33(27,28)32-13;/h8-9,13-14,17H,3-7H2,1-2H3,(H,27,28)(H2,20,21,22,24,26);/q;+1/p-1/t9-,13-,14-,17-;/m1./s1
• InChI key: MGBPJXVWDGGLKI-GBIKJYCISA-M

설명

일반 설명

Cell-permeable cGMP analog that preferentially activates protein kinase G. Inhibits thrombin stimulated arachidonic acid release in human platelets.

Cell-permeable cGMP analog that preferentially activates protein kinase G. Inhibits thrombin-stimulated arachidonic acid release in human platelets.

생화학적/생리학적 작용

Cell permeable: yes

Primary Target
Cell-permeable cGMP analog that preferentially activates protein kinase G.

Product does not compete with ATP.

Reversible: no

경고

Toxicity: Standard Handling (A)

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

기타 정보

Sane, D.C., et al. 1989. Biochem. Biophys. Res. Commun.165, 708.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable