17-283
Rac1 Activation Assay Kit
Non-radioactive Rac1 Activation Assay Kit can be used to precipitate Rac1-GTP from cell lysates & detection by a Rac1 specific monoclonal antibody.
동의어(들):
Activation Assay Kit, Rac1 Activity Kit, Rac1 Assay Kit
로그인조직 및 계약 가격 보기
크기 선택
1 KIT
₩1,484,742
₩1,484,742
예상 입고일2025년 3월 27일세부사항
모든 사진(1)
크기 선택
보기 변경
1 KIT
₩1,484,742
About This Item
UNSPSC 코드:
12161503
eCl@ss:
32161000
NACRES:
NA.32
₩1,484,742
예상 입고일2025년 3월 27일세부사항
추천 제품
Quality Level
종 반응성
human, rat, mouse
제조업체/상표
Upstate®
기술
activity assay: suitable
affinity binding assay: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
유전자 정보
human ... RAC1(5879)
일반 설명
Non-radioactive Rac1 Activation Assay Kit can be used to precipitate Ras-related C3 botulinum toxin substrate 1 (Rac1)-GTP from cell lysates and detected by a Rac1 specific monoclonal antibody. Rac1 belongs to the Ras superfamily of small guanosine triphosphatases (GTPases). It is expressed in two major forms such as an inactive GDP-bound form and an active GTP-bound form. Rac1 is involved in influencing several physiological conditions by interacting with effectors that activate several signaling cascades.[1] The RAC1 gene is located on the human chromosome at 7p22.1.[2]
애플리케이션
Rac1 Activation Assay Kit has been used in the detection of active Ras-related C3 botulinum toxin substrate 1 (Rac1) in brain homogenates of mice and humans by immunoblotting.[3]
성분
Anti-Rac1, clone 23A8 (Cat.# 05-389)
Mg2+ Lysis/Wash Buffer, 5X (Cat.# 20-168)
100X GTPγS, 10mM (Cat.# 20-176)
100X GDP, 100mM (Cat.# 20-177)
Rac/cdc42 Assay Reagent (PAK1 PBD, agarose) (Cat.# 14-325)
Mg2+ Lysis/Wash Buffer, 5X (Cat.# 20-168)
100X GTPγS, 10mM (Cat.# 20-176)
100X GDP, 100mM (Cat.# 20-177)
Rac/cdc42 Assay Reagent (PAK1 PBD, agarose) (Cat.# 14-325)
품질
Routinely evaluated by precipitating Rac-GTP from 3T3 cell lysates that had been loaded with GTPγS. The precipitated Rac-GTP was detected by immunoblot analysis using anti-Rac.
결합
Replaces: SGT425
법적 정보
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1
Storage Class Code
10 - Combustible liquids
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
The role of mechanical stretching in the activation and localization of adhesion proteins and related intracellular molecules.
Boccafoschi, F, et al.
Journal of Cellular Biochemistry, 112, 1403-1409 (2011)
The survival kinase Mirk/dyrk1B is activated through Rac1-MKK3 signaling.
Kideok Jin, Seunghwan Lim, Stephen E Mercer, Eileen Friedman
The Journal of Biological Chemistry null
rs12977 of RAC1 is associated with the progress of gastric cancer in Iranian population
Javani A, et al.
Gene Reports, 23, 101069-101069 (2021)
Incorporation of CXCR4 into membrane lipid rafts primes homing-related responses of hematopoietic stem/progenitor cells to an SDF-1 gradient.
Marcin Wysoczynski, Ryan Reca, Janina Ratajczak, Magda Kucia, Neeta Shirvaikar et al.
Blood null
Anti-arrhythmic surgery for atrioventricular junctional and atrioventricular re-entrant tachycardia--a report of six cases.
Koo, C C, et al.
Annals of the Academy of Medicine, Singapore, 19, 67-72 (1990)
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.
