164610
p-Aminophenylmercuric Acetate
An organomercurial agent used for the activation of latent MMPs in vitro. Acts by facilitating the loss of the enzyme propeptide domain through an autolytic cleavage known as the cysteine switch.
동의어(들):
p-Aminophenylmercuric Acetate, APMA
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
실험식(Hill 표기법):
C8H9HgNO2
CAS Number:
Molecular Weight:
351.75
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.77
가격 및 재고 정보를 현재 이용할 수 없음 고객지원팀으로 연락바랍니다.
추천 제품
Quality Level
설명
RTECS - OV5550000
분석
≥90% (HPLC)
양식
solid
제조업체/상표
Calbiochem®
저장 조건
OK to freeze
색상
yellow
solubility
0.1 M NaOH: 10 mg/mL
DMSO: 10 mg/mL
배송 상태
ambient
저장 온도
10-30°C
SMILES string
[Hg+]c1ccc(cc1)N.[O-]C(=O)C
InChI
1S/C6H6N.C2H4O2.Hg/c7-6-4-2-1-3-5-6;1-2(3)4;/h2-5H,7H2;1H3,(H,3,4);/q;;+1/p-1
InChI key
RXSUFCOOZSGWSW-UHFFFAOYSA-M
일반 설명
An organomercurial agent used for the activation of latent MMPs in vitro. Acts by facilitating the loss of the enzyme propeptide domain through an autolytic cleavage known as the cysteine switch.
An organomercurial agent used for the activation of latent matrix metalloproteinases (MMPs) in vitro. Acts by facilitating the loss of the enzyme propeptide domain through an autolytic cleavage known as the cysteine switch.
생화학적/생리학적 작용
Cell permeable: no
Primary Target
Activation of latent MMPs in vitro
Activation of latent MMPs in vitro
Product does not compete with ATP.
Reversible: no
경고
Toxicity: Highly Toxic (H)
재구성
Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 month at 4°C.
기타 정보
Chen, J.-M., et al. 1991. J. Biol. Chem. 266, 5113.
Marcy, A.I., et al. 1991. Biochemistry30, 6476.
Stricklin, G.P., et al. 1983. Biochemistry22, 61.
Marcy, A.I., et al. 1991. Biochemistry30, 6476.
Stricklin, G.P., et al. 1983. Biochemistry22, 61.
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
법적 정보
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Saskia V Vijver et al.
Frontiers in immunology, 12, 733561-733561 (2021-10-26)
The tumor microenvironment (TME) is a complex structure comprised of tumor, immune and stromal cells, vasculature, and extracellular matrix (ECM). During tumor development, ECM homeostasis is dysregulated. Collagen remodeling by matrix metalloproteinases (MMPs) generates specific collagen fragments, that can be
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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