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Merck
모든 사진(1)

주요 문서

16-272

Sigma-Aldrich

Anti-acetyl Lysine Antibody, clone 4G12, agarose conjugate

clone 4G12, Upstate®, from mouse

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크기 선택

100 μG
₩808,752

₩808,752


예상 입고일2025년 5월 02일세부사항



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100 μG
₩808,752

About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

₩808,752


예상 입고일2025년 5월 02일세부사항


생물학적 소스

mouse

Quality Level

항체 형태

purified antibody

항체 생산 유형

primary antibodies

클론

4G12, monoclonal

종 반응성(상동성에 의해 예측)

all

제조업체/상표

Upstate®

기술

immunoprecipitation (IP): suitable

배송 상태

wet ice

타겟 번역 후 변형

acetylation (Lys)

특이성

Recognizes acetyl lysine-containing proteins including histones.

면역원

A mixture of chemically acetylated antigens. Clone 4G12.

애플리케이션

Detect acetyl Lysine with Anti-acetyl Lysine Antibody, clone 4G12, agarose conjugate (Mouse Monoclonal Antibody), that has been shown to work in IP.
Research Category
Signaling

Epigenetics & Nuclear Function
Research Sub Category
General Post-translation Modification

Histones

특징 및 장점

Format: Gel Immobilized

품질

Routinely evaluated by immunoprecipitating

표적 설명

varies depending upon the protein being detected

저장 및 안정성

1 year at 4°C from date of shipment. DO NOT FREEZE.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Yan Liu et al.
Journal of proteome research, 20(5), 2596-2606 (2021-04-02)
Decreased cellular NAD+ levels are causally linked to aging and aging-associated diseases. NAD+ precursors in oxidized form such as nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) have gained much attention and been well studied for their ability to restore NAD+
A Villagra et al.
Methods in enzymology, 573, 161-181 (2016-07-04)
Histone deacetylase assays were first developed in the 1970s, and subsequently refined in the 1990s with the cloning of HDAC enzymes. Most of these early assays, relying on traditional in vitro chemical methodologies, are still applicable today. More recently, however
N Munshi et al.
Molecular cell, 2(4), 457-467 (1998-11-11)
The transcriptional coactivators CBP and P/CAF are required for activation of transcription from the IFN beta enhanceosome. We show that CBP and P/CAF acetylate HMG I(Y), the essential architectural component required for enhanceosome assembly, at distinct lysine residues, causing distinct
Acetylation of general transcription factors by histone acetyltransferases.
Imhof, A, et al.
Current Biology, 7, 689-692 (1997)
Fei Yue et al.
Aging, 7(10), 839-853 (2015-11-06)
Autophagy controls and executes the turnover of abnormally aggregated proteins. MAP1S interacts with the autophagy marker LC3 and positively regulates autophagy flux. HDAC4 associates with the aggregation-prone mutant huntingtin protein (mHTT) that causes Huntington's disease, and colocalizes with it in

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