KLH-conjugated peptide (ARK[pS]TGGKAPRKQL- C) corresponding to amino acids 7-20 of human histone H3.
애플리케이션
Anti-phospho-Histone H3 (Ser10) Antibody, biotin conjugate is a Rabbit Polyclonal Antibody for detection of Histone H3 phosphorylated at serine 10. This purified mAb, also known as H3S10p,is biotinylated, published in peer reviewed journals and has been validated in WB, ICC.
Research Category Epigenetics & Nuclear Function
Research Sub Category Histones
품질
routinely evaluated in immunocytochemistry by immunostaining chromatin in HeLa cells undergoing mitosis
물리적 형태
PBS, pH 7.4, with 0.05% sodium azide.
Protein A purified
저장 및 안정성
6 months at 4°C
법적 정보
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
One of the major challenges in the development of alternative carcinogenicity assays is the prediction of non-genotoxic carcinogens. The variety of non-genotoxic cancer pathways complicates the search for reliable parameters expressing their carcinogenicity. As non-genotoxic and genotoxic carcinogens have different
Journal of applied toxicology : JAT, 35(3), 319-326 (2014-06-27)
To investigate hydrophobic test compounds in toxicological studies, solvents like dimethylsulfoxide (DMSO) are inevitable. However, using these solvents, the interpretation of test compound-induced responses can be biased. DMSO concentration guidelines are available, but are mostly based on acute exposures involving
Human molecular genetics, 19(23), 4560-4572 (2010-09-17)
Crooked tail (Cd) mice bear a gain-of-function mutation in Lrp6, a co-receptor for canonical WNT signaling, and are a model of neural tube defects (NTDs), preventable with dietary folic acid (FA) supplementation. Whether the FA response reflects a direct influence
Human molecular genetics, 22(21), 4267-4281 (2013-06-19)
Low-density lipoprotein receptor related protein 6 (Lrp6) mutational effects on neurulation were examined using gain (Crooked tail, Lrp6(Cd)) and loss (Lrp6(-)) of function mouse lines. Two features often associated with canonical Wnt signaling, dorsal-ventral patterning and proliferation, were no different
Development (Cambridge, England), 141(17), 3388-3398 (2014-08-21)
Lens epithelial cells and early lens fiber cells contain the typical complement of intracellular organelles. However, as lens fiber cells mature they must destroy their organelles, including nuclei, in a process that has remained enigmatic for over a century, but