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Merck
모든 사진(1)

문서

14-477-M

Sigma-Aldrich

Cdk5/p35 Protein, active, 10 µg

Active complex of recombinant full length human Cdk5 containing & N-terminal His6-tag & recombinant full-length human p35 containing an N-terminal GST-tag, for use in Kinase Assays.

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About This Item

UNSPSC 코드:
12352202
eCl@ss:
32160405
NACRES:
NA.26

생물학적 소스

human

Quality Level

재조합

expressed in baculovirus infected Sf21 cells

분자량

Mw 34 kDa (cdk5)
Mw 61 kDa (p35 with GST-tag)

제조업체/상표

Upstate®

기술

activity assay: suitable (kinase)

NCBI 수납 번호

UniProt 수납 번호

일반 설명

Complex of recombinant fulllength human cdk5 containing and N-terminal His6-tag and recombinant full-length human p35 containing an N-terminal GST-tag
Product Source: Both are expressed by baculovirus in Sf21 insect cells

생화학적/생리학적 작용

Protein Target: CDK5/p35
Target Sub-Family: CMGC

포장

Also available in 250μg size as catalog # 14-477M - Call for pricing and availability.

품질

routinely evaluated by phosphorylation of Histone H1

물리적 형태

Ni-NTA agarose

저장 및 안정성

1 year at -70°C

기타 정보

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Ward G Walkup et al.
The Journal of biological chemistry, 290(8), 4908-4927 (2014-12-24)
synGAP is a neuron-specific Ras and Rap GTPase-activating protein (GAP) found in high concentrations in the postsynaptic density (PSD) fraction from the mammalian forebrain. We have previously shown that, in situ in the PSD fraction or in recombinant form in
Ward G Walkup et al.
eLife, 5 (2016-10-21)
SynGAP is a Ras/Rap GTPase-activating protein (GAP) that is a major constituent of postsynaptic densities (PSDs) from mammalian forebrain. Its α1 isoform binds to all three PDZ (PSD-95, Discs-large, ZO-1) domains of PSD-95, the principal PSD scaffold, and can occupy

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