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Merck
모든 사진(1)

주요 문서

14-309

Sigma-Aldrich

PCAF Protein, Active, 50 µg

PCAF recombinant GST fusion protein, for use in Histone Acetyltransferase Assays. (HAT).

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About This Item

UNSPSC 코드:
12352202
eCl@ss:
32160405
NACRES:
NA.32
가격 및 재고 정보를 현재 이용할 수 없음 고객지원팀으로 연락바랍니다.

재조합

expressed in E. coli

Quality Level

분자량

Mw 79 kDa

제조업체/상표

Upstate®

기술

activity assay: suitable (histone acetyltransferase (HAT))

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

일반 설명

Product Source: expressed in E. Coli corresponding to amino acids 352-832

품질

routinely evaluated by acetylation of core histones in vitro

기타 정보

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1


시험 성적서(COA)

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문서 라이브러리 방문

Prabhat Kumar Purbey et al.
Molecular and cellular biology, 29(5), 1321-1337 (2008-12-24)
Special AT-rich binding protein 1 (SATB1) acts as a global regulator of gene expression by recruiting various corepressor or coactivator complexes, thereby establishing a unique chromatin structure at its genomic targets in a context-dependent manner. Although SATB1 acts predominantly as
Matteo Savoia et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(3), 4107-4123 (2018-12-12)
The epigenetic enzyme p300/CBP-associated factor (PCAF) belongs to the GCN5-related N-acetyltransferase (GNAT) family together with GCN5. Although its transcriptional and post-translational function is well characterized, little is known about its properties as regulator of cell metabolism. Here, we report the
Giosalba Burgio et al.
Journal of enzyme inhibition and medicinal chemistry, 31(sup3), 75-82 (2016-07-09)
Histones and polyamines are important determinants of the chromatin structure. Histones form the core of nucleosome particles and their modification by acetylation of N-terminal tails is involved in chromatin structural changes and transcriptional regulation. Polyamines, including spermidine, are also targets
Steven E Lang et al.
Oncogene, 22(18), 2836-2841 (2003-05-14)
The adenovirus E1A oncoprotein stimulates cell growth and inhibits differentiation by deregulating the normal transcription program via interaction with positive and negative cellular effectors. E1A associates with transcriptional regulatory complexes containing p400 and TRRAP involved in chromatin remodeling and decondensation.
R L Schiltz et al.
The Journal of biological chemistry, 274(3), 1189-1192 (1999-01-09)
A number of transcriptional coactivators possess intrinsic histone acetylase activity, providing a direct link between hyperacetylated chromatin and transcriptional activation. We have determined the core histone residues acetylated in vitro by recombinant p300 and PCAF within mononucleosomes. p300 specifically acetylates

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