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Merck
모든 사진(1)

문서

14-155

Sigma-Aldrich

Histone H1 Protein, 20 mg

Purified bovine Histone H1 protein for use as a substrate in histone modification assays (HAT, HDAC, DNMT) and chromatin assembly studies.

동의어(들):

Linker Histone H1

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About This Item

UNSPSC 코드:
12352202
eCl@ss:
32160405
NACRES:
NA.32

생물학적 소스

bovine

Quality Level

분자량

Mw 32 kDa

제조업체/상표

Upstate®

기술

activity assay: suitable (kinase)

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

일반 설명

H1 and related linker histones are important both for maintenance of higher-order chromatin structure and for the regulation of gene expression. Nucleosomal stabilization is provided through the binding of histone H1 to the nucleosomal dyad and the linker DNA entering and exiting the core particle. Additional experimental evidence illustrates the influence of histone H1 on chromatin arrangement and compaction. The family of histone H1 proteins contains five somatic variants (H1.1, H1.2, H1.3, H1.4 and H1.5) which are expressed in nearly all cell types.
Product Source: Lysine rich fraction from calf thymus

품질

Routinely evaluated by Kinase assay using cdk2/cyclin A, active (14-448) to phosphorylate Histone H1.

물리적 형태

Sterilized through a 0.2 micron membrane filter

저장 및 안정성

1 year at -20°C

기타 정보

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
This product is derived from bovine source. Export of this product to certain countries may be restricted. Please contact Customer Service or your local distributor to inquire about product availability and export options.

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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B Ouyang et al.
The Journal of biological chemistry, 272(45), 28646-28651 (1997-11-14)
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