1.04672

Synthechol^® Synthetic Cholesterol

EMPROVE^® EXPERT, Ph. Eur., BP, JP, NF

• 동의어(들): Cholesterol, 3β-Hydroxy-5-cholestene, 5-Cholesten-3β-ol
• 실험식(Hill 표기법): C₂₇H₄₆O
• CAS Number: 57-88-5
• Molecular Weight: 386.65
• Beilstein: 1915888
• MDL number: MFCD00003646
• UNSPSC 코드: 12352104

속성

• 생물학적 소스: synthetic
• Quality Level: 500
• Agency: BP; JP; NF; Ph. Eur.
• 제품 라인: EMPROVE^® EXPERT
• 형태: powder
• bp: 360 °C (lit.)
• mp: ~141 °C; 147-149 °C (lit.)
• density: 1.067 g/mL at 25 °C (lit.)
• 적합성: suitable for (Suitable for formulation and manufacturing use)
• 응용 분야: advanced drug delivery; controlled release; liquid formulation; parenterals; pharmaceutical
• 저장 온도: 15-25°C
• SMILES string: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
• InChI key: HVYWMOMLDIMFJA-DPAQBDIFSA-N

설명

일반 설명

A GMP-scalable process which yields a high-quality lipid is essential to lipidic drug product development and manufacturing. We are highly specialized in synthesizing top-quality GMP lipids for pharmaceutical applications and gene therapy, focusing on tailored manufacturing to meet your specific needs. We also offer an off-the-shelf catalog with optimized stability, solubility, and handling characteristics.
Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

애플리케이션

Cholesterol is a major component of all biological cell membranes and is used as a stabilizer of lipid bilayers in many lipid-based formulations for the delivery of different APIs, such as small molecules and nucleic acids.
Synthetic cholesterol, Ph Eur, BP, JP, NF is ultra-pure and therefore suitable for divers formulations applications. Due to low batch to batch variability, very high purity, and lack of biological components, this product is optimal for highly sensitive applications such as nucleic acid delivery.
With a newly optimized manufacturing process, this product is available in quantities from grams to tons to support your development progress. A dual sourcing option is also possible.

생화학적/생리학적 작용

Major component of all biological membranes; ~25% of total brain lipid is cholesterol.

법적 정보

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

SyntheChol is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

The substance 1.04672 has no REACH registration because the only supported use is the use in medicinal products for human or veterinary use or in food or feedingstuffs according to article 2 of the REACH Regulation (EC) No 1907/2006.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable