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Merck
모든 사진(1)

문서

06-996

Sigma-Aldrich

Anti-phospho-Kip1 (Thr187) Antibody

Upstate®, from rabbit

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

affinity purified immunoglobulin

항체 생산 유형

primary antibodies

클론

polyclonal

정제법

affinity chromatography

종 반응성

human, mouse, rat

제조업체/상표

Upstate®

기술

western blot: suitable

동형

IgG

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

타겟 번역 후 변형

phosphorylation (pThr187)

유전자 정보

human ... CDKN1B(1027)

특이성

phosphorylated Kip1

면역원

KLH-conjugated, synthetic peptide (C-PNAGSVEQ[pT]PKK) corresponding to amino acids 179-190 of human Kip1

애플리케이션

Anti-phospho-Kip1 (Thr187) Antibody is a high quality Rabbit Polyclonal Antibody for the detection of phospho-Kip1 (Thr187) & has been validated in WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

품질

routinely evaluated by immunoblot on a HeLa cell RIPA lysate

표적 설명

27kDa

물리적 형태

0.2M Tris, 0.15 M NaCl, 0.1mM EDTA, 0.05% sodium azide before the addition of glycerol to 30%
Immunoaffinity Chromatography

저장 및 안정성

1 year at -20°C

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1


시험 성적서(COA)

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문서 라이브러리 방문

p27KIP1, an inhibitor of cyclin-dependent kinases.
Koff, A and Polyak, K
Progress in Cell Cycle Research, 1, 141-147 (1995)
Oncostatin M induces growth arrest by inhibition of Skp2, Cks1, and cyclin A expression and induced p21 expression.
Halfter, H; Friedrich, M; Resch, A; Kullmann, M; Stogbauer, F; Ringelstein, EB; Hengst, L
Cancer Research null
J Kato
Frontiers in bioscience : a journal and virtual library, 4, D787-D792 (1999-11-30)
The first gap phase (G1) in the mammalian cell cycle plays a pivotal role in determining whether or not cells are to initiate DNA replication. Progression through G1 phase and transition into S phase are positively and negatively regulated by
G Wolf
Kidney international, 56(4), 1262-1265 (1999-10-03)
There are two fundamentally different growth responses for cells comprising the nephron: hyperplasia or hypertrophy. Cells that progress through the normal cell cycle double their DNA content and eventually divide during mitosis. Those cells that hypertrophy stop the growth process
Shuichan Xu et al.
The Journal of biological chemistry, 282(21), 15462-15470 (2007-04-06)
p27, an important cell cycle regulator, blocks the G(1)/S transition in cells by binding and inhibiting Cdk2/cyclin A and Cdk2/cyclin E complexes (Cdk2/E). Ubiquitination and subsequent degradation play a critical role in regulating the levels of p27 during cell cycle

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