추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
polyclonal
종 반응성
mouse, human
제조업체/상표
Upstate®
기술
immunoprecipitation (IP): suitable
western blot: suitable
동형
IgG
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... LAT(27040)
mouse ... Lat(16797)
특이성
Recognizes both forms of LAT.
면역원
GST-tagged fusion protein corresponding to residues 31-233 of human LAT
애플리케이션
Anti-LAT Antibody detects level of LAT & has been published & validated for use in IP & WB.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Immunoglobulins & Immunology
품질
routinely evaluated by immunoblot on RIPA lysates from Jurkat cells
표적 설명
36/38 kDa
물리적 형태
Format: Purified
Protein A Purified immunoglobulin in 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, and 0.05% sodium azide.
Protein A purified
저장 및 안정성
Stable for 1 year at 2-8°C from date of receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
분석 메모
Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
적합한 제품을 찾을 수 없으신가요?
당사의 제품 선택기 도구.을(를) 시도해 보세요.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Displacement of linker for activation of T cells from the plasma membrane due to redox balance alterations results in hyporesponsiveness of synovial fluid T lymphocytes in rheumatoid arthritis.
S I Gringhuis, A Leow, E A Papendrecht-Van Der Voort, P H Remans, F C Breedveld, C L Verweij
Journal of immunology (Baltimore, Md. : 1950) (1950)
Assessment of caspase mediated degradation of linker for activation of T cells (LAT) at a single cell level.
Klossowicz, Mikolaj, et al.
Journal of Immunological Methods, 389, 9-17 (2013)
Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70.
Wange, R L, et al.
The Journal of Biological Chemistry, 270, 18730-18733 (1995)
B S Wilson et al.
The Journal of cell biology, 154(3), 645-658 (2001-08-08)
In mast cells, cross-linking the high-affinity IgE receptor (Fc(epsilon)RI) initiates the Lyn-mediated phosphorylation of receptor ITAMs, forming phospho-ITAM binding sites for Syk. Previous immunogold labeling of membrane sheets showed that resting Fc(epsilon)RI colocalize loosely with Lyn, whereas cross-linked Fc(epsilon)RI redistribute
T Harder et al.
The Journal of cell biology, 151(2), 199-208 (2000-10-19)
Activation of T cell antigen receptor (TCR) induces tyrosine phosphorylations that mediate the assembly of signaling protein complexes. Moreover, cholesterol-sphingolipid raft membrane domains have been implicated to play a role in TCR signal transduction. Here, we studied the assembly of
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.
