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Merck
모든 사진(1)

문서

05-920

Sigma-Aldrich

Anti-NR2B Antibody, clone BWJHL

clone BWJHL, Upstate®, from mouse

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

BWJHL, monoclonal

종 반응성

human, rat

제조업체/상표

Upstate®

기술

western blot: suitable

동형

IgG

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

타겟 번역 후 변형

unmodified

유전자 정보

mouse ... Grin2B(14812)

특이성

NR2B

면역원

GST fusion protein corresponding to residues 934-1457 of rat NR2B. Clone BWJHL.

애플리케이션

Anti-NR2B Antibody, clone BWJHL detects level of NR2B & has been published & validated for use in WB.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins

Neurodegenerative Diseases

품질

routinely evaluated by immunoblot on rat brain microsomal preparations (Catalog#12-144)

표적 설명

Mr 180kDa

물리적 형태

Format: Purified
Protein G Purified

저장 및 안정성

stable 2 years at -20°C from date of shipment

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Brain-derived neurotrophic factor-tyrosine kinase B pathway mediates NMDA receptor NR2B subunit phosphorylation in the supraoptic nuclei following progressive dehydration.
Carre?o, FR; Walch, JD; Dutta, M; Nedungadi, TP; Cunningham, JT
Journal of Neuroendocrinology null
Peter D Cole et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 19(16), 4446-4454 (2013-07-09)
To test whether memantine can prevent methotrexate-induced cognitive deficits in a preclinical model. After noting that methotrexate exposure induces prolonged elevations of the glutamate analog homocysteic acid (HCA) within cerebrospinal fluid, we tested whether intrathecal injection of HCA would produce
Jackson J Cone et al.
PloS one, 8(3), e58251-e58251 (2013-03-22)
The development of diet-induced obesity (DIO) can potently alter multiple aspects of dopamine signaling, including dopamine transporter (DAT) expression and dopamine reuptake. However, the time-course of diet-induced changes in DAT expression and function and whether such changes are dependent upon
Sarah A Monaco et al.
Frontiers in cellular neuroscience, 12, 16-16 (2018-02-17)
Glycogen synthase kinase 3β (GSK3β) is a highly conserved serine/threonine kinase that has been implicated in both psychiatric and neurodegenerative diseases including schizophrenia, bipolar disorder, and Alzheimer's disease; therefore regulating its activity has become an important strategy for treatment of
Meng-Lin Li et al.
Neurobiology of learning and memory, 140, 52-61 (2017-02-19)
Schizophrenia (SCZ) is a neurodevelopmental psychiatric disorder, in which cognitive function becomes disrupted at early stages of the disease. Although the mechanisms underlying cognitive impairments remain unclear, N-methyl-D-aspartate receptors (NMDAR) hypofunctioning in the prefrontal cortex (PFC) has been implicated. Moreover

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