Assayed in therapeutic drug monitoring to ensure patients remain within the drug’s therapeutic range, mycophenolic acid is an immunosuppressant drugand the active metabolite of the prodrug mycophenolate mofetil. This internalstandard is suitable for quantification of mycophenolic acid levels in wholeblood or plasma by LC-MS/MS for therapeutic drug monitoring and other clinical or diagnostic applications.
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CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Heterochromatin is a specialized form of chromatin that restricts access to DNA and inhibits genetic processes, including transcription and recombination. In Neurospora crassa, constitutive heterochromatin is characterized by trimethylation of lysine 9 on histone H3, hypoacetylation of histones, and DNA
Pancreatic cancer is one of the most lethal malignancies and has an extremely poor diagnosis and prognosis. The development of resistance to gemcitabine is still a major challenge. The long noncoding RNA PVT1 was reported to be involved in carcinogenesis
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