LM2144

Sphingosine-1-Phosphate (d17:1)

Avanti Research^™ - A Croda Brand

• 동의어(들): heptadeca-sphing-4-enine-1-phosphate
• 실험식(Hill 표기법): C₁₇H₃₆NO₅P
• CAS Number: 474923-27-8
• Molecular Weight: 365.45
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 양식: ethanol solution
• 포장: pkg of 1 × 1 mL (LM2144-1EA)
• 제조업체/상표: Avanti Research^™ - A Croda Brand
• 농도: ~10 μg/mL (Refer to C of A for lot specific concentration.)
• 응용 분야: lipidomics; metabolomics
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: CCCCCCCCCCCC/C=C/[C@@]([H])(O)[C@]([NH3+])([H])COP([O-])(O)=O
• InChI: 1S/C17H36NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(19)16(18)15-23-24(20,21)22/h13-14,16-17,19H,2-12,15,18H2,1H3,(H2,20,21,22)/b14-13+/t16-,17+/m0/s1
• InChI key: VITGNIYTXHNNNE-LHMZYYNSSA-N

설명

일반 설명

Sphingosine-1-phosphate (S1P) is a sphingolipid found in yeast, plants and mammals[1] and is produced in endothelial cells.[2] It is a cellular metabolite and signalling lipid in mammalian cells.[1] S1P is synthesized by sphingosine kinases from sphingosine.[3] It is a high affinity ligand for sphingosine-1-phosphate receptor (S1P1-5).[4]

생화학적/생리학적 작용

Sphingosine 1-phosphate (S1P) plays a vital role as a secondary messenger in physiological processes.[3] It is implicated in the pathogenesis of osteoporosis, cancer, atherosclerosis and diabetes.[3] S1P regulates skin dendritic cells and keratinocytes[2]

포장

2 mL Amber Glass Sealed Ampule (LM2144-1EA)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• 픽토그램: GHS02,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H225,H319
• 예방조치 성명서: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point (°F): 55.4 °F - closed cup
• Flash Point (°C): 13.0 °C - closed cup