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문서

890860P

Avanti

14:0 TAP

Avanti Research - A Croda Brand 890860P, powder

동의어(들):

1,2-dimyristoyl-3-trimethylammonium-propane (chloride salt)

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About This Item

실험식(Hill 표기법):
C34H68NO4Cl
CAS Number:
Molecular Weight:
590.36
UNSPSC 코드:
12352211
NACRES:
NA.25

형태

powder

포장

pkg of 1 × 200 mg (890860P-200mg)

제조업체/상표

Avanti Research - A Croda Brand 890860P

지질 유형

cationic lipids
transfection

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[Cl-]

일반 설명

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is a saturated cationic lipid with a positively charged headgroup. It has an alkyl chain length with 14 carbon atoms.

애플리케이션

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is suitable for:
  • the preparation of cationic liposomes
  • reconstitution of bacteriorhodopsin (BR) and proteorhodopsin (PR) into liposomes
  • composing lipid–styrene maleic acid (SMA) complexes
  • liposome preparation by double emulsion method

생화학적/생리학적 작용

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is useful for bicelle formation. Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.

포장

5 mL Amber Glass Screw Cap Vial (890860P-200mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


시험 성적서(COA)

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Styrene maleic acid copolymers (SMA) form discoidal lipid nanoparticles (lipid nanodisks) that mimic plasma high-density lipoproteins. We have previously prepared and characterized lipid nanodisks composed of SMA and the neutral phospholipid 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). In the present study, we tested whether
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Saeki D, et al.
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In order to investigate the relationship between lipid structure and liposome-mediated gene transfer, we have studied biophysical parameters and transfection properties of monocationic DOTAP analogs, systematically modified in their non-polar hydrocarbon chains. Stability, size and (by means of anisotropy profiles)
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