860811P

12:0(2R-OH) Ceramide

Avanti Research^™ - A Croda Brand 860811P, powder

• 동의어(들): N-(2′-(R)-hydroxylauroyl)-D-erythro-sphingosine
• 실험식(Hill 표기법): C₃₀H₅₉NO₄
• CAS Number: 1246298-44-1
• Molecular Weight: 497.79
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 형태: powder
• 포장: pkg of 1 × 5 mg (860811P-5mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 860811P
• 지질 유형: sphingolipids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCC)=O)CO

설명

일반 설명

Ceramides containing 2-hydroxy fatty acid (hFA) are found primarily in the epidermis. 12:0(2R-OH) Ceramide is a 2R hydroxylated lauric acid-containing ceramide.

생화학적/생리학적 작용

Hydroxy fatty acid (hFA)-sphingolipids play a specific role in cell signaling. Synthesis of hFA-ceramides requires fatty acid 2-hydroxylase (FA2H). Mutations of this key enzyme are associated with the development of nervous system disorders such as leukodystrophy and spastic paraparesis in humans. hFA-ceramides are essential for the epidermal permeability barrier function. The mechanism of action for an antitumor drug, PM02734 involves hFA-ceramides in the cell membrane.

포장

5 mL Amber Glass Screw Cap Vial (860811P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3