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860667P

Avanti

4E,8Z-Sphingadiene

Avanti Research - A Croda Brand 860667P, powder

동의어(들):

(2S,3R,4E,8Z)-2-aminooctadec-4,8-diene-1,3-diol

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크기 선택

1 MG
₩363,472

₩363,472


예상 입고일2025년 3월 31일세부사항


벌크 견적 요청

크기 선택

보기 변경
1 MG
₩363,472

About This Item

실험식(Hill 표기법):
C18H35NO2
CAS Number:
Molecular Weight:
297.48
MDL number:
UNSPSC 코드:
12352211
NACRES:
NA.25

₩363,472


예상 입고일2025년 3월 31일세부사항


벌크 견적 요청

양식

powder

포장

pkg of 1 × 1 mg (860667P-1mg)

제조업체/상표

Avanti Research - A Croda Brand 860667P

지질 유형

sphingolipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

OC[C@@](N)([H])[C@]([H])(O)/C=C/CC/C=C\CCCCCCCCC

InChI

1S/C18H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h10-11,14-15,17-18,20-21H,2-9,12-13,16,19H2,1H3/b11-10-,15-14+/t17-,18+/m0/s1

InChI key

RTQVJTLVVBJRJG-NZDSQIAKSA-N

일반 설명

4E,8Z-Sphingadiene is a unique sphingoid base containing C18 chain, with trans double bond at C-4 and cis double bond at C8.[1] It is widely present in plant tissues, but very minimal in mammals.[2]

애플리케이션

4E,8Z-Sphingadiene has been used as an standard in liquid chromatography with tandem mass spectrometry (LC-MS-MS) method for quantitation of chemopreventive sphingadienes in food products and biological samples.[3]

생화학적/생리학적 작용

Sphingadienes are growth-inhibitory sphingoid bases, which play a vital role in apoptosis and cell signaling.[4][5] Sphingadienes isolated from plants exhibit anti-inflammatory properties by inhibiting tumor necrosis factor α (TNF α) activity.[5]

포장

5 mL Amber Glass Screw Cap Vial (860667P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

No data available

Flash Point (°C)

No data available


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시험 성적서(COA)

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문서 라이브러리 방문

J H Suh et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1061-1062, 292-299 (2017-08-05)
Colorectal cancer (CRC) is a leading cause of cancer mortality. Diet has a significant influence on colon cancer risk. Identifying chemopreventive agents, dietary constituents, practices and/or diet supplements that promote gut health and reduce the incidence of intestinal neoplasias and
An LC/MS/MS method for quantitation of chemopreventive sphingadienes in food products and biological samples
Suh JH, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1061, 292-299 (2017)
Structure of plasma sphingadienine
Renkonen O and Hirvisalo EL
Journal of Lipid Research, 10(6), 687-693 (1969)
O Renkonen et al.
Journal of lipid research, 10(6), 687-693 (1969-11-01)
The dienic long-chain base (sphingadienine) of human plasma sphingomyelins has been identified as d-erythro-1,3-dihydroxy-2-amino-4-trans-14-cis-octadecadiene. A similar sphingosine was also detected in plasma sphingomyelins of rat, rabbit, and cat. The key reaction in the structural studies was partial reduction of sphingadienine
Occurrence, structure elucidation, biosynthesis, functions and synthesis of sphingadienes
U Abeytunga T
Mini-Reviews in Organic Chemistry, 12(3), 282-292 (2015)

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