콘텐츠로 건너뛰기
Merck
모든 사진(2)

주요 문서

모든 문서 보기

850539P

Avanti

Facade™-EPC

3α-hydroxy-7α,12α-di-(((2-(trimethylamino)ethyl)phosphoryl)ethyloxy)-cholane, powder

동의어(들):

FA-7

로그인조직 및 계약 가격 보기

크기 선택

25 MG
₩318,710

₩318,710

구입 가능 여부는 고객센터에 문의하십시오.
벌크 견적 요청
모든 사진(2)

크기 선택

보기 변경
25 MG
₩318,710

About This Item

실험식(Hill 표기법):
C38H74N2O11P2
CAS Number:
1429405-99-1
Molecular Weight:
796.95
UNSPSC 코드:
12352211
NACRES:
NA.25

₩318,710

구입 가능 여부는 고객센터에 문의하십시오.
벌크 견적 요청

분석

>99% (TLC)

양식

powder

분자량

796.95 g/mol

포장

pkg of 1 × 25 mg (850539P-25mg)

제조업체/상표

Avanti Research™ - A Croda Brand 850539P

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@@]12[C@]([C@](CC[C@@H](O)C3)(C)[C@]3([H])C[C@H]2OCCOP(OCC[N+](C)(C)C)([O-])=O)([H])C[C@H](OCCOP(OCC[N+](C)(C)C)([O-])=O)[C@@]4(C)[C@@]1([H])CC[C@@H]4[C@H](C)CCC

InChI

1S/C38H74N2O11P2/c1-11-12-28(2)31-13-14-32-36-33(27-35(38(31,32)4)47-22-24-51-53(44,45)49-20-18-40(8,9)10)37(3)16-15-30(41)25-29(37)26-34(36)46-21-23-50-52(42,43)48-19-17-39(5,6)7/h28-36,41H,11-27H2,1-10H3/t28-,29+,30-,31-,32+,33+,34-,35+,36+,37+,38-/m1/s

InChI key

RTNFJBQUBTXGHR-HECRFRQFSA-N

애플리케이션

Facade™-EPC has been used to produce bicelles for nuclear magnetic resonance (NMR) experiments.[1][2] It may be used in crystallization of cytochrome P450 2B subfamily proteins, CYP2B35 and CYP2B37.[3]

생화학적/생리학적 작용

Facade™ EPC/FA-7 (3α-hydroxy-7α,12α-di-(((2-(trimethylamino)ethyl)phosphoryl)ethyloxy)-cholane) having phosphocholine groups helps in preparing smaller micelles than the facial amphiphiles (FAs) with nonionic sugar groups.[4]
Facade™ is a mild rim forming surfactants, used in the synthesis of isotropic bicelles which prevents unfolding of soluble globular domains of large membrane proteins.[2]

포장

5 mL Amber Glass Screw Cap Vial (850539P-25mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC
Facade is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 문서 section.

도움이 필요하시면 연락하세요. 고객 지원 부서

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Faccade detergents as bicelle rim-forming agents for solution NMR spectroscopy
Mineev KS, et al.
Nanotechnology Reviews, 6(1), 93-103 (2017)
Structure-function analysis of mammalian CYP2B enzymes using 7-substituted coumarin derivatives as probes: utility of crystal structures and molecular modeling in understanding xenobiotic metabolism
Shah MB, et al.
Molecular Pharmacology, 89(4), 435-445 (2016)
Phase Transitions in Small Isotropic Bicelles
Kot EF, et al.
Langmuir, 34(11), 3426-3437 (2018)
Sung Chang Lee et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(13), E1203-E1211 (2013-03-13)
Amphiphile selection is a critical step for structural studies of membrane proteins (MPs). We have developed a family of steroid-based facial amphiphiles (FAs) that are structurally distinct from conventional detergents and previously developed FAs. The unique FAs stabilize MPs and
Designing facial amphiphiles for the stabilization of integral membrane proteins.
Qinghai Zhang et al.
Angewandte Chemie (International ed. in English), 46(37), 7023-7025 (2007-08-11)
모든 관련된 서류 보기

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.