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Merck
모든 사진(2)

문서

850346C

Avanti

14:1 (Δ9-Cis) PC

1,2-dimyristoleoyl-sn-glycero-3-phosphocholine, chloroform

동의어(들):

1,2-di-(9Z-tetradecenoyl)-sn-glycero-3-phosphocholine; PC(14:1(9Z)/14:1(9Z))

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About This Item

실험식(Hill 표기법):
C36H68NO8P
CAS Number:
Molecular Weight:
673.90
UNSPSC 코드:
51191904
NACRES:
NA.25

분석

>99% (TLC)

형태

liquid

포장

pkg of 1 × 2.5 mL (850346C-25mg)
pkg of 2 × 4 mL (850346C-200mg)

제조업체/상표

Avanti Research - A Croda Brand 850346C

농도

10 mg/mL (850346C-25mg)
25 mg/mL (850346C-200mg)

지질 유형

cardiolipins
phospholipids

배송 상태

dry ice

저장 온도

−20°C

일반 설명

Phosphatidylcholine (PC) belongs to the class of glycerophospholipid. It is the prime cellular phospholipid.
Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

애플리케이션

14:1 (Δ9-Cis) PC has been used in the liposome preparation. It has also been used as an internal standard for the extraction of lipids from the interstitial fractions of lung tissues for electrospray ionisation-mass spectrometry (ESI-MS) analysis.

생화학적/생리학적 작용

Phosphatidylcholine (PC) contributes to the membrane structure. Each cell type and tissue maintain a unique PC profile. PC plays a key role in cell signaling. Disruption in the homeostasis of PC leads to cell death in mammalian cells. PC is present in bile and aids in lipid emulsification in the diet. It is known to reduce cholesterol and triglyceride levels. It is administered for treating fat embolism and cardiac ischemia. Monounsaturated PC 14:1 (Δ9-Cis) is known to inhibit cell proliferation in different cell lines.
Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

포장

5 mL Clear Glass Sealed Ampule (850346C-200mg)
5 mL Clear Glass Sealed Ampule (850346C-25mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

픽토그램

Skull and crossbonesHealth hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

표적 기관

Liver,Kidney, Respiratory system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point (°F)

does not flash

Flash Point (°C)

does not flash


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

The Membranes of Cells (2016)
Phosphatidylcholine and cell death
Cui Z and Houweling M
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1585(2-3), 87-96 (2002)
Jiao Cao et al.
Nature communications, 10(1), 5668-5668 (2019-12-13)
Biological nanopores are capable of resolving small analytes down to a monoatomic ion. In this research, tetrachloroaurate(III), a polyatomic ion, is discovered to bind to the methionine residue (M113) of a wild-type α-hemolysin by reversible Au(III)-thioether coordination. However, the cylindrical
Bilayer thickness and curvature influence binding and insertion of a pHLIP peptide
Karabadzhak AG, et al.
Biophysical Journal, 114(9), 2107-2115 (2018)
Integrative Medicine - E-Book (2017)

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