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Merck
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주요 문서

640014P

Avanti

Ceramide Synthase (CerS5/CerS6) Assay Kit

Avanti Research - A Croda Brand

동의어(들):

Ceramide Synthase (CerS5/CerS6) Assay Kit, CerS5/S6 Assay Kit

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About This Item

UNSPSC 코드:
12161503

양식

powder

사용

sufficient for ~275 reactions

제조업체/상표

Avanti Research - A Croda Brand

배송 상태

dry ice

저장 온도

−20°C

일반 설명

The CerS Assay Kit provides an easy to use assay for measuring CerS activity in biological samples. This Kit offers the advantage of a short assay time requiring only small amounts of biological material while eliminating TLC as a separation technique with its attendant degradation of NBD sphinganine.

생화학적/생리학적 작용

Ceramide synthase (cerS) catalyzes the acylation of sphinganine (dihydrosphingosine) to yield dihydroceramide and sphingosine to yield ceramide.[1] There are six cerS (cerS1-6), which differ in their specificity to yield ceramides of different chain length.[2] Ceramide is a key intermediate in sphingolipid metabolism and an key signaling molecule.[3]

포장

Kit contains:
0.3mg 16:0 fatty acyl-CoA
0.1mg NBD Sphinganine

저장 및 안정성

Note: this product should be stored at -20° for up to 6 months.

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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제품 번호
설명
SDS

  • 810206PNBD Sphinganine, omega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R)-2-aminooctadecane-1,3-diol, powderSDS

  • 870716P16:0 Coenzyme A, Avanti Research - A Croda Brand 870716P, powderSDS

Storage Class Code

10 - Combustible liquids


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

The equilibrium between long and very long chain ceramides is important for the fate of the cell and can be influenced by co-expression of CerS.
Hartmann D, et al.
The International Journal of Biochemistry & Cell Biology, 45(7), 1195-1203 (2013)
When do Lasses (longevity assurance genes) become CerS (ceramide synthases)? Insights into the regulation of ceramide synthesis.
Pewzner-Jung Y, et al.
The Journal of Biological Chemistry, 281(35), 25001-25005 (2006)
Mammalian Ceramide Synthases
Michal L, et al.
IUBMB Life, 62(5), 347?356-347?356 (2010)

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