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Merck
모든 사진(4)

주요 문서

640006P

Avanti

DMABA-d6 NHS Ester

Avanti Research - A Croda Brand

동의어(들):

4-(dimethylamino)benzoic acid N-hydroxysuccinimide ester-d6

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About This Item

실험식(Hill 표기법):
C13H8D6N2O4
CAS Number:
Molecular Weight:
268.30
UNSPSC 코드:
12352211
NACRES:
NA.25

설명

4-[di(methyl-d3)amino]-2,5-dioxo-1-pyrrolidinyl ester benzoic acid-d6

분석

>99% (TLC)

양식

powder

포장

pkg of 1 × 1 mg (640006P-1mg)

제조업체/상표

Avanti Research - A Croda Brand

배송 상태

dry ice

저장 온도

−20°C

SMILES string

O=C(ON(C(CC1)=O)C1=O)C2=CC=C(N(C([2H])([2H])[2H])C([2H])([2H])[2H])C=C2

일반 설명

The DMABA NHS ester reagents were developed by Dr. Robert Murphy′s laboratory at the University of Colorado in order to create PE derivatives where all subclasses and potentially oxidized products could be universally detected using a common precursor ion in the positive ion mode by Mass Spectrometry.

생화학적/생리학적 작용

Deuterium enriched 4-(dimethylamino) benzoic acid (DMABA) N-hydroxysuccinimide (NHS) ester reagents (d0, d4, d6, d10) derivatize the primary amine group of lipids, such as glycerophosphoethanolamine (PE) lipid species.[1]

포장

5 mL Amber Glass Screw Cap Vial (640006P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Marko Kosicek et al.
International journal of molecular sciences, 14(1), 1310-1322 (2013-01-12)
Brain is one of the richest organs in lipid content. Phospholipids (glycerophospholipids and sphingolipids) are important building blocks of cell membranes, which provide an optimal environment for protein interactions, trafficking and function. Because of that, alterations in their cellular levels
Yukiko Ueda et al.
Nutrition research (New York, N.Y.), 28(4), 239-244 (2008-12-17)
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn disease (CD), is a disorder characterized by diffuse inflammation of the gastrointestinal tract. The immune response and inflammation are mediated by polyunsaturated fatty acids and influenced by dietary fats and
Gilbert O Fruhwirth et al.
Biochimica et biophysica acta, 1772(7), 718-736 (2007-06-16)
Oxidized lipids are generated from (poly)unsaturated diacyl- and alk(en)ylacyl glycerophospholipids under conditions of oxidative stress. The great variety of reaction products is defined by the degree of modification, hydrophobicity, chemical reactivity, physical properties and biological activity. The biological activities of
Karin A Zemski Berry et al.
European journal of mass spectrometry (Chichester, England), 16(3), 463-470 (2008-01-01)
Recently, a derivative of PE, namely the 4-(dimethylamino)benzoic acid derivative has been developed with various isotope labeled variants that provided a universal precursor ion scan for diacyl, ether and plasmalogen PE lipids that can not be accomplished otherwise. This derivative
Karin A Zemski Berry et al.
Analytical chemistry, 81(16), 6633-6640 (2010-03-27)
A set of four (D(0), D(4), D(6), and D(10)) deuterium enriched 4-(dimethylamino)benzoic acid (DMABA) N-hydroxysuccinimide (NHS) ester reagents was developed that react with the primary amine group of glycerophosphoethanolamine (PE) lipids to create derivatives where all subclasses of DMABA labeled

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