분석
≥98%
양식
powder
항생제 활성 스펙트럼
parasites
동작 모드
enzyme | inhibits
SMILES string
OC(=O)CC(O)(CC(O)=O)C(O)=O.CCN(CC)C(=O)N1CCN(C)CC1
InChI
1S/C10H21N3O.C6H8O7/c1-4-12(5-2)10(14)13-8-6-11(3)7-9-13;7-3(8)1-6(13,5(11)12)2-4(9)10/h4-9H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
InChI key
PGNKBEARDDELNB-UHFFFAOYSA-N
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신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 4 Oral
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
B K Singh et al.
European journal of medicinal chemistry, 43(12), 2717-2723 (2008-03-15)
A series of 2-sulfanyl-6-methyl-1,4-dihydropyrimidines (8-21) were synthesized in good yields by alkylation of 5-methyl-6-phenyl-2-thioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid ethyl esters (2-7) with different alkyl or aralkyl halides in the presence of a combination of anhydrous K(2)CO(3) and catalytic amount of tetrabutyl ammonium bromide.
Koneni V Sashidhara et al.
Bioorganic & medicinal chemistry letters, 22(4), 1527-1532 (2012-01-31)
A series of 3,6-epoxy [1,5]dioxocines were synthesized and evaluated for their antifilarial activity against adult parasites of human lymphatic filarial parasite Brugia malayi (sub-periodic strain) in vitro. Out of these, six compounds (4a-f) possessed improved in vitro anti-filarial activity and
Debidas Ray et al.
The Indian journal of medical research, 134, 79-82 (2011-08-03)
Observation of an increased frequency of an intermediate deficiency of serum alpha1-antitrypsin (α1-AT) in patients with Tropical Pulmonary Eosinophilia (TPE) was earlier reported. Though the possibility of existence of an acquired deficiency was suggested, without phenotyping a hereditary α1-AT deficiency
Eugene T Richardson et al.
Journal of travel medicine, 19(3), 183-185 (2012-04-26)
We present a case of Loa loa infection in a patient, 21 years after visiting an endemic area for only 4 days. To our knowledge, this case represents the longest time for the diagnosis of loiasis to be made post-exposure
Delynn M Moss et al.
The American journal of tropical medicine and hygiene, 85(2), 229-237 (2011-08-05)
A multiplex bead assay (MBA) was used to analyze serum samples collected longitudinally from children enrolled in a drug trial for treatment of filariasis in Leogane, Haiti. Recombinant antigens Bm14 and Bm33 from Brugia malayi, third polar tube protein (PTP3)
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