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25 MG
₩733,236
About This Item
실험식(Hill 표기법):
C46H72Cl4N3O8P
CAS Number:
Molecular Weight:
967.86
UNSPSC 코드:
12161503
NACRES:
NA.21
추천 제품
Quality Level
분석
≥90%
양식
solid
색상
orange to dark red
저장 온도
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@H](OC(CCCC1=CC(Cl)=C(C(Cl)=C1)/N=N/C2=C(C=C(C=C2Cl)CCCC)Cl)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O
InChI
1S/C46H72Cl4N3O8P/c1-6-8-10-11-12-13-14-15-16-17-18-19-20-21-22-26-43(54)58-34-38(35-60-62(56,57)59-29-28-53(3,4)5)61-44(55)27-23-25-37-32-41(49)46(42(50)33-37)52-51-45-39(47)30-36(24-9-7-2)31-40(45)48/h30-33,38H,6-29,34-35H2,1-5H3/b52-51+/t38-/m1/s1
InChI key
FLGJQVLXMDITOI-MYZMGNDKSA-N
일반 설명
The NanoFabTx Photoactivatable Lipid, redAzoPC is a red-light photoswitchable lipid for controlled and targeted drug delivery. The tetra-ortho-chloro-azobenzene of redAzoPC can be isomerized from the cis to the trans conformation at 660 nm light. LNPs prepared using the NanoFabTx™ Photoactivatable Lipid, redAzoPC result in controlled drug release following deep red light irradiation.
애플리케이션
Lipid nanoparticle and liposome drug delivery systems
특징 및 장점
- Similar drug loading, encapsulation efficiency, size, and polydispersity to non-photoswitchable lipids
- Light-induced drug delivery
- Targeted and controlled release
- Overcomes limitations associated to UV-switchable lipids
법적 정보
NANOFABTX is a trademark of Sigma-Aldrich Co. LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
Nisha Chander et al.
Small (Weinheim an der Bergstrasse, Germany), 17(21), e2008198-e2008198 (2021-04-22)
Encapsulation of small molecule drugs in long-circulating lipid nanoparticles (LNPs) can reduce toxic side effects and enhance accumulation at tumor sites. A fundamental problem, however, is the slow release of encapsulated drugs from these liposomal systems at the disease site
Tufan K Mukhopadhyay et al.
Current opinion in pharmacology, 63, 102202-102202 (2022-03-13)
Many aspects of cell signaling are controlled by lipids. Several signaling lipids have been functionalized with an azobenzene photoswitch to control underlying signaling dynamics with light. Herein, we provide an overview of signaling photolipids developed to date focusing on their
Johannes Morstein et al.
Chembiochem : a European journal of chemical biology, 22(1), 73-83 (2020-08-14)
Photoswitchable lipids are emerging tools for the precise manipulation and study of lipid function. They can modulate many aspects of membrane biophysics, including permeability, fluidity, lipid mobility and domain formation. They are also very useful in lipid physiology and enable
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