933899
N-(2-Hydroxy) propyl-3-trimethylammonium chitosan chloride
degree of quaternization 50%
동의어(들):
Chioisan, HTCC, Quaternized Chitosan, Solube chitosan, TMC, Trimethyl chitoan
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933899-2G
₩552,160
About This Item
Linear Formula:
(C12H25N2O5Cl)n(C8H13NO5)m
UNSPSC 코드:
12352201
NACRES:
NA.21
추천 제품
![Poly[bis(2-chloroethyl) ether-alt-1,3-bis[3-(dimethylamino)propyl]urea] quaternized, solution 62 wt. % in H2O](/deepweb/assets/sigmaaldrich/product/structures/139/843/f0b4a2ac-de44-4fb5-ab36-a700daaf8aa5/640/f0b4a2ac-de44-4fb5-ab36-a700daaf8aa5.png)
설명
NMR: Conforms to structure
Quality Level
양식
(solid, chunks or fiber)
색상
white to off-white
저장 온도
2-8°C
일반 설명
Chitosan offers remarkable biological properties; it has been widely used in drug delivery and tissue engineering applications. Chitosan has good mucoadhesive properties due to its positive charge, which increases the adhesion to mucosa and facilitates drug penetration. Also, chitosan possesses hemostatic properties, which makes it a good candidate for wound dressing applications[1].
The quaternization of the primary amine increases the water solubility of chitosan and keeps chitosan soluble over a wide pH range. Cationically modified chitosan such as N-(2-Hydroxy)propyl-3-trimethyl ammonium chitosan chloride (HTCC) also imparts excellent antibacterial activity[2] and immuno-enhancing[3] characteristics. HTCC also used in gene delivery applications[4]
The quaternization of the primary amine increases the water solubility of chitosan and keeps chitosan soluble over a wide pH range. Cationically modified chitosan such as N-(2-Hydroxy)propyl-3-trimethyl ammonium chitosan chloride (HTCC) also imparts excellent antibacterial activity[2] and immuno-enhancing[3] characteristics. HTCC also used in gene delivery applications[4]
애플리케이션
Small molecule and nucleic acid delivery
Tissue engineering
Antibacterial coatings
Tissue engineering
Antibacterial coatings
특징 및 장점
Water soluble
Cationically modified
Naturally derived and biocompatible
Cationically modified
Naturally derived and biocompatible
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Hamid Hamedi et al.
Carbohydrate polymers, 199, 445-460 (2018-08-26)
Advanced development of chitosan hydrogels has led to new drug delivery systems that can release their active ingredients in response to environmental stimuli. This review considers more recent investigation of chitosan hydrogel preparations and the application of these preparations for
Kai Zhao et al.
Vaccines, 9(9) (2021-09-29)
Porcine parvovirus (PPV) is the most important infectious agent causing infertility in pigs, which can be prevented by routine vaccination. Successful vaccination depends on the association with potent adjuvants that can enhance the immunogenicity of antigen and activate the immune
Microbiocidal activity of chitosan-N-2-hydroxypropyl trimethyl ammonium chloride
Chi W, et al.
Journal of Applied Polymer Science, 103, 3851-3856 (2007)
Bo Xiao et al.
Colloids and surfaces. B, Biointerfaces, 91, 168-174 (2011-11-23)
A series of N-(2-hydroxy)propyl-3-trimethyl ammonium chitosan chloride (HTCC) samples with various degrees of quaternization ranging from 12.4 to 43.7% was synthesized. The structures and properties of HTCC were investigated by FT-IR, (1)H NMR, conductometric titration and XRD analysis. It was
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