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Merck
모든 사진(1)

주요 문서

902659

Sigma-Aldrich

Amino-PEG6-t-butyl ester

동의어(들):

tert-Butyl 1-amino-3,6,9,12,15,18-hexaoxahenicosan-21-oate, H2N-PEG6-CH2CH2COOtBu

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250 MG
₩302,166
1 G
₩1,106,046

₩302,166


예상 입고일2025년 5월 22일세부사항


벌크 견적 요청

크기 선택

보기 변경
250 MG
₩302,166
1 G
₩1,106,046

About This Item

실험식(Hill 표기법):
C19H39NO8
CAS Number:
Molecular Weight:
409.51
MDL number:
UNSPSC 코드:
51171641
NACRES:
NA.22

₩302,166


예상 입고일2025년 5월 22일세부사항


벌크 견적 요청

양식

liquid

반응 적합성

reagent type: cross-linking reagent

refractive index

n/D 1.4562

density

1.06581 g/mL

작용기

amine
ester

저장 온도

−20°C

SMILES string

NCCOCCOCCOCCOCCOCCOCCC(OC(C)(C)C)=O

InChI

1S/C19H39NO8/c1-19(2,3)28-18(21)4-6-22-8-10-24-12-14-26-16-17-27-15-13-25-11-9-23-7-5-20/h4-17,20H2,1-3H3

InChI key

QGSFECNPSLZGGT-UHFFFAOYSA-N

관련 카테고리

애플리케이션

This heterobifunctional, PEGylated crosslinker features an amino group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Amino-PEG6-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

법적 정보

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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