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Merck
모든 사진(1)

주요 문서

779776

Sigma-Aldrich

Methyl-β-cyclodextrin

Wacker Chemie AG, ≥95.0% cyclodextrin basis (calculated)

동의어(들):

Cavasol® W7 M, Methyl-beta-cyclodextrin

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크기 선택

100 G
₩560,382
500 G
₩1,458,352
10 KG
₩3,348,790

₩560,382


예상 입고일2025년 4월 21일세부사항


벌크 견적 요청

크기 선택

보기 변경
100 G
₩560,382
500 G
₩1,458,352
10 KG
₩3,348,790

About This Item

CAS Number:
MDL number:
UNSPSC 코드:
12352201
NACRES:
NA.22

₩560,382


예상 입고일2025년 4월 21일세부사항


벌크 견적 요청

Quality Level

분석

≥95.0% cyclodextrin basis (calculated)

양식

powder

제조업체/상표

Wacker Chemie AG

라벨링 범위

1.6-1.9 molar substitution

불순물

≤0.2% unsubstituted cyclodextrin
≤0.2% volatile organics
≤2% chloride

손실

≤7.0% loss on drying

mp

180-182 °C (lit.)

SMILES string

O1C2OC(C(OC3OC(C(OC4OC(C(OC5OC(C(OC6OC(C(OC7OC(C(OC8OC(C1C(C8OC)O)COC)C(C7OC)O)COC)C(C6OC)O)COC)C(C5OC)O)COC)C(C4OC)O)COC)C(C3OC)O)COC)C(C2OC)O)COC

InChI

1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3

InChI key

QGKBSGBYSPTPKJ-UHFFFAOYSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Methyl-β-cyclodextrin (M-β-CD) can be used as a reactant to prepare ternary inclusion complex of diclofenac (DCF) in the presence of monoethanolamine (MEA). This complex improves the percutaneous absorption of DCF in human skin.[1] It can also be used to form an inclusion complex with olanzapine (OLP) to increase its solubility for efficient drug delivery.[2]

기타 정보

For R&D Use

법적 정보

Cavasol is a registered trademark of Wacker Chemie AG

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

368.6 °F

Flash Point (°C)

187 °C


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문서 라이브러리 방문

Inclusion complex of methyl-β -cyclodextrin and olanzapine as potential drug delivery system for schizophrenia
de Freitas MR, et al.
Carbohydrate Polymers, 89(4), 1095-1100 (2012)
María Julia Mora et al.
European journal of medicinal chemistry, 45(9), 4079-4088 (2010-06-23)
Here, we describe the chemical characterization of the inclusion complex between diclofenac (DCF) and methyl-beta-cyclodextrin (M-beta-CD) in the presence or absence of monoethanolamine (MEA). Several techniques were used to analyze the complex both in solution and in the solid state.
Sara Rodríguez-Acebes et al.
The Biochemical journal, 420(2), 305-315 (2009-03-06)
Cholesterol homoeostasis is critical for cell viability and proliferation. The SREBP (sterol regulatory element-binding protein) pathway is crucial for the maintenance of cholesterol homoeostasis. This pathway is controlled by cholesterol and cholesterol-derived oxysterols. J774 cells cannot convert desmosterol into cholesterol
Mario Menschikowski et al.
Cancer cell international, 11, 4-4 (2011-02-16)
Increasing evidences show that beyond its role in coagulation, endothelial protein C receptor (EPCR) interferes with carcinogenesis. Pro-carcinogenic effects of EPCR were linked with a raised generation of activated protein C (aPC) and anti-apoptotic signalling. This study was carried out
Laurie Hamtiaux et al.
PloS one, 6(10), e26823-e26823 (2011-11-03)
The antitumoral properties of endocannabinoids received a particular attention these last few years. Indeed, these endogenous molecules have been reported to exert cytostatic, apoptotic and antiangiogenic effects in different tumor cell lines and tumor xenografts. Therefore, we investigated the cytotoxicity

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