추천 제품
형태
liquid
반응 적합성
reaction type: click chemistry
reagent type: cross-linking reagent
작용기
alkyne
amine
저장 온도
−20°C
SMILES string
NCCOCCOCCOCCOCC#C
InChI
1S/C11H21NO4/c1-2-4-13-6-8-15-10-11-16-9-7-14-5-3-12/h1H,3-12H2
InChI key
QDLPAHLHHBCWOW-UHFFFAOYSA-N
애플리케이션
Heterobifunctional linker enabling the connection of an azide containing compound or biomolecule to one with a carboxylic acid. The amine group can be linked to a carboxylic acid through standard coupling procedures (EDC, product #39391, etc...) and the terminal alkyne will react with azides via copper-catalyzed 1,3-dipolar cycloaddition click chemistry. The hydrophilic PEG spacer adds to the water solubility of this reagent, allowing for easy modification of carboxylic acid containing biomolecules such as antibodies, proteins and peptides with the terminal alkyne. The PEG spacer also reduces aggregation of modified proteins stored in solution by adding hydrophilic character.
Amino-PEG4-alkyne may be used to synthesize alkynyl-functionalized iron oxide nanoparticles (IONPs) for preparing glycopolymer-based iron oxide nanoparticles (GIONs) for potential bioscience applications.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
Strain-promoted azide?alkyne cycloaddition for protein?protein coupling in the formation of a bis-hemoglobin as a copper-free oxygen carrier
Organic & Biomolecular Chemistry (2016)
Facile fabrication of glycopolymer-based iron oxide nanoparticles and their applications in the carbohydrate?lectin interaction and targeted cell imaging.
Polym. Chem., 7(6), 1337-1344 (2016)
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