686344

4,4,5,5-Tetramethyl-1,3,2-dioxaphospholane 2-oxide

95%

• 동의어(들): 2-Oxo-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane, 4,4,5,5-Tetramethyl-1,3,2-dioxaphospholan-2-ol, HASPO-1, Phosphonic acid pinacol ester, Pinacol phosphonate
• 실험식(Hill 표기법): C₆H₁₃O₃P
• CAS Number: 16352-18-4
• Molecular Weight: 164.14
• MDL number: MFCD09836231
• UNSPSC 코드: 12352005
• PubChem Substance ID: 329761040

속성

• 분석: 95%
• 양식: powder
• 반응 적합성: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• mp: 99-106 °C
• 작용기: phosphine
• SMILES string: CC1(C)O[PH](=O)OC1(C)C
• InChI: 1S/C6H13O3P/c1-5(2)6(3,4)9-10(7)8-5/h10H,1-4H3
• InChI key: QPONEGYFSLRCLJ-UHFFFAOYSA-N

설명

애플리케이션

• Preligand in palladium-catalyzed Kumada cross-coupling reactions of aryl tosylates with Grignard reagents
• Catalyst for reversible chain transfer polymerizations

Reactant for:

• Synthesis of oxapalladacycle as catalyst for Markovnikov-type addition
• Preparation of palladium(II) complexes as catalysts for Heck cross-coupling reactions
• Preparation of palladium catalysts for asymmetric hydrogenation of a-keto phosphonates
• Hydrophosphorylation of alkenes, dienes and enynes in the presence of rhodium catalysts

Air-stable preligand for Pd-catalyzed Kumada-type cross-couplings.[1]

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H312,H319
• 예방조치 성명서: P264 - P280 - P302 + P352 + P312 - P305 + P351 + P338 - P337 + P313 - P362 + P364
• Hazard Classifications: Acute Tox. 4 Dermal - Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves