663190

Ethyl 5-methylindole-2-carboxylate

97%

• 동의어(들): 5-Methylindole-2-carboxylic acid ethyl ester, NSC 30928
• 실험식(Hill 표기법): C₁₂H₁₃NO₂
• CAS Number: 16382-15-3
• Molecular Weight: 203.24
• MDL number: MFCD00022703
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24884618
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: 97%
• 양식: solid
• mp: 160-164 °C
• 작용기: ester
• SMILES string: CCOC(=O)c1cc2cc(C)ccc2[nH]1
• InChI: 1S/C12H13NO2/c1-3-15-12(14)11-7-9-6-8(2)4-5-10(9)13-11/h4-7,13H,3H2,1-2H3
• InChI key: KMVFKXFOPNKHEM-UHFFFAOYSA-N

설명

일반 설명

Ethyl 5-methylindole-2-carboxylate (5-Methylindole-2-carboxylic acid ethyl ester) is an indole derivative. Indole ring system is an important building block or intermediate in the synthesis of many pharmaceutical agents. It is formed during the Fischer indolization of ethyl pyruvate 2-[2-(methanesulfonyloxy)-4-methyl]phenylhydrazine.[1]

애플리케이션

• Reactant for synthesis of oxazino[4,3-a]indoles via cascade addition-cyclization reactions
• Reactant for preparation of indolecarboxamides as cannabinoid CB1 receptor antagonists
• Reactant for preparation of indole-3-propionic acids as antiinflammatory and analgesic agents
• Reactant for Friedel-Crafts acylation with nitrobenzoyl chloride
• Reactant for oximation reactions

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)