638013

4-Diphenylphosphanylbenzoic acid, 2-(trimethylsilyl)ethyl ester solution

0.5 M in THF

• 실험식(Hill 표기법): C₂₄H₂₇O₂PSi
• CAS Number: 566190-45-2
• Molecular Weight: 406.53
• MDL number: MFCD07369722
• UNSPSC 코드: 12352108
• PubChem Substance ID: 24882904

속성

• 반응 적합성: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• 농도: 0.5 M in THF
• density: 0.925 g/mL at 25 °C
• 작용기: phosphine
• SMILES string: C[Si](C)(C)CCOC(=O)c1ccc(cc1)P(c2ccccc2)c3ccccc3
• InChI: 1S/C24H27O2PSi/c1-28(2,3)19-18-26-24(25)20-14-16-23(17-15-20)27(21-10-6-4-7-11-21)22-12-8-5-9-13-22/h4-17H,18-19H2,1-3H3
• InChI key: QTYUNPJLGFKKRV-UHFFFAOYSA-N

설명

애플리케이션

4-Diphenylphosphanyl-benzoic acid 2-trimethylsilanyl-ethyl ester (DPPBE) was developed as an efficient alternative to triphenylphosphine in the Mitsunobu reaction since the phosphine oxide formed during the reaction can be easily removed during workup.[1]

Reagent for:

• Synthesis of alkenes
• Methylation of aldehydes
• Mitsunobu reactions

안전성 정보

• 픽토그램: GHS02,GHS08,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H225,H319,H335,H351
• 예방조치 성명서: P210 - P280 - P305 + P351 + P338 - P370 + P378 - P403 + P235
• Hazard Classifications: Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• 표적 기관: Respiratory system
• 보충제 위험성: EUH019
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point (°F): -4.0 °F - closed cup
• Flash Point (°C): -20 °C - closed cup