556815

3-Ethyl-4-methyl-3-pyrrolin-2-one

97%

• 실험식(Hill 표기법): C₇H₁₁NO
• CAS Number: 766-36-9
• Molecular Weight: 125.17
• MDL number: MFCD00173861
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24879585
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: 97%
• mp: 100-104 °C (lit.)
• SMILES string: CCC1=C(C)CNC1=O
• InChI: 1S/C7H11NO/c1-3-6-5(2)4-8-7(6)9/h3-4H2,1-2H3,(H,8,9)
• InChI key: YCTNTSVMJWIYTQ-UHFFFAOYSA-N

설명

일반 설명

3-Ethyl-4-methyl-3-pyrrolin-2-one, a five-membered α,β-unsaturated lactam derivative, has various applications in medicinal chemistry. It can be synthesized by employing following as starting materials:[1]

• allylamine, via palladium(II)-assisted cyclization
• 4-methoxybenzylamine, via a ring-closing-metathesis strategy
• 3-ethyl-1-(4-methoxybenzyl)-4-methyl-1,5-dihydro-2H-pyrrol-2- one

애플리케이션

3-Ethyl-4-methyl-3-pyrrolin-2-one (3-Ethyl-4-methyl-1,5-dihydro-2H-pyrrol-2-one) may be employed as a precursor for the synthesis of glimepiride (antidiabetic drug) and its derivatives (sulfonylurea drugs).[1] It may also be employed for the preparation of 2-ethyl-3-methyl-(10H)-
dipyrrin-1-one.[2]

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)