549207

5-Amino-3-(4-methylphenyl)pyrazole

97%

• 동의어(들): 3-Amino-5-(4-methylphenyl)-1H-pyrazole
• 실험식(Hill 표기법): C₁₀H₁₁N₃
• CAS Number: 78597-54-3
• Molecular Weight: 173.21
• MDL number: MFCD00084887
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24879068
• NACRES: NA.22

속성

• 분석: 97%
• 양식: solid
• mp: 148-151 °C (lit.)
• SMILES string: Cc1ccc(cc1)-c2cc(N)[nH]n2
• InChI: 1S/C10H11N3/c1-7-2-4-8(5-3-7)9-6-10(11)13-12-9/h2-6H,1H3,(H3,11,12,13)
• InChI key: GVPFRVKDBZWRCZ-UHFFFAOYSA-N

설명

일반 설명

5-Amino-3-(4-methylphenyl)pyrazole or 5-amino-3-(4-methylphenyl)-1H-pyrazole belongs to a family of 5-aminopyrazole derivatives, which are bioactive agents. They find a wide range of applications in the pharmaceutical and agrochemical industries.[1]

애플리케이션

5-Amino-3-(4-methylphenyl)pyrazole may be used:

• As a starting material for preparing 2,5-bis(4-methylphenyl)-7-phenyl-6,7-dihydropyrazolo[1,5-a]pyrimidine-3,6-dicarbaldehyde, a potential precursor for building bioactive fused polycyclic pyrazoles.[2]
• To synthesize 4-hetarylpyrazolo[1,5-a][1,3,5]triazines under microwave conditions and in the absence of solvent.[3]
• To synthesize 5-cyano-6,7-dihydro-3-(4-methylphenyl)-6-oxo-1H-pyrazolo[3,4-b]pyridine-4-carboxylates by reacting with dialkyl dicyanofumarates.[4]

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves