465313

1-Methylindole-3-carboxylic acid

97%

• 실험식(Hill 표기법): C₁₀H₉NO₂
• CAS Number: 32387-21-6
• Molecular Weight: 175.18
• MDL number: MFCD01321244
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24870267

속성

• 분석: 97%
• mp: 197-200 °C (dec.) (lit.)
• SMILES string: Cn1cc(C(O)=O)c2ccccc12
• InChI: 1S/C10H9NO2/c1-11-6-8(10(12)13)7-4-2-3-5-9(7)11/h2-6H,1H3,(H,12,13)
• InChI key: HVRCLXXJIQTXHC-UHFFFAOYSA-N

설명

일반 설명

1-Methylindole-3-carboxylic acid is an indole derivative that can be prepared by the oxidation of 1-methylindole-3-aldehyde with alkaline potassium permanganate.

애플리케이션

• Reactant for preparation of bisindolyl pyrimidinones analogs of PKC inhibitor LY333531
• Reactant for preparation of (heteroaryl)(carboxamido)arylpyrrole derivatives as Cdc7 kinase inhibitors, antitumor and antiproliferative agents
• Reactant for preparation of (pyrrolidinylmethoxy)cyclohexanecarboxylic acids as antigen-4 (VLA-4) antagonists
• Reactant for preparation of EphB3 receptor tyrosine kinase inhibitors
• Reactant for preparation of pyrazolodiazepine derivatives as human P2X7 receptor antagonists
• Reactant for preparation of potent nonpeptidic urotensin II receptor agonists
• Reactant for preparation of pyrrolizidine esters, amides, and ureas as 5-HT4 receptor ligands

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves