324124

2-Chloro-1,3,2-benzodioxaphosphorin-4-one

95%

• 동의어(들): SalPCl, Salicyl chlorophosphite
• 실험식(Hill 표기법): C₇H₄ClO₃P
• CAS Number: 5381-99-7
• Molecular Weight: 202.53
• Beilstein: 1311951
• MDL number: MFCD00013353
• UNSPSC 코드: 12352005
• PubChem Substance ID: 24859425
• NACRES: NA.22

속성

• 분석: 95%
• 양식: solid
• 반응 적합성: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• bp: 127-128 °C/11 mmHg (lit.)
• mp: 36-40 °C (lit.)
• 작용기: phosphine
• 저장 온도: 2-8°C
• SMILES string: ClP1OC(=O)c2ccccc2O1
• InChI: 1S/C7H4ClO3P/c8-12-10-6-4-2-1-3-5(6)7(9)11-12/h1-4H
• InChI key: BVOITXUNGDUXRW-UHFFFAOYSA-N

설명

애플리케이션

2-Chloro-1,3,2-benzodioxaphosphorin-4-one is used as a reagent:

• In the phosphorylation and phosphitylation of alcohols.[1][2]
• In the formation of H-phosphonates which are commonly utilized in the synthesis of nucleotides.[1][2]
• To synthesize nucleoside triphosphates by treating with acyl protected nucleoside.[3]

안전성 정보

• 픽토그램: GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H314
• 예방조치 성명서: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• 보충제 위험성: EUH014
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point (°F): 235.4 °F - closed cup
• Flash Point (°C): 113 °C - closed cup
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges