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Merck
모든 사진(2)

문서

220930

Sigma-Aldrich

Potassium nitrosodisulfonate

동의어(들):

Dipotassium nitrosodisulfonate, Fremy’s salt

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About This Item

Linear Formula:
(KSO3)2NO
CAS Number:
Molecular Weight:
268.33
EC Number:
MDL number:
UNSPSC 코드:
12352000
PubChem Substance ID:
NACRES:
NA.22

형태

powder

반응 적합성

reagent type: oxidant

저장 온도

2-8°C

SMILES string

[K+].[K+].[O]N(S([O-])(=O)=O)S([O-])(=O)=O

InChI

1S/2K.H2NO7S2/c;;2-1(9(3,4)5)10(6,7)8/h;;(H,3,4,5)(H,6,7,8)/q2*+1;/p-2

InChI key

IHSLHAZEJBXKMN-UHFFFAOYSA-L

일반 설명

Potassium nitrosodisulfonate is an oxidizing reagent that can be used to convert phenols, naphthols, and anilines to quinones, benzylic alcohols to aldehydes or ketones, and amino acids to α-keto acids. It can also be used for the preparation of heterocyclic quinones and oxidative aromatization.

애플리케이션

Potassium nitrosodisulfonate can be used as an oxidizing reagent for the oxidation of:
  • Aromatic amines to their corresponding quinones.
  • Hydroethidine to 2-hydroxyethidium.
  • Tyrosine to o-quinones.

픽토그램

FlameExclamation mark

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Water-react 1

보충제 위험성

Storage Class Code

4.3 - Hazardous materials which set free flammable gases upon contact with water

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

J. Wood Chem. Technol., 9, 491-491 (1989)
S Pötsch et al.
FEBS letters, 374(1), 95-99 (1995-10-23)
The rate of reduction of the tyrosyl radical in the small subunit of ribonucleotide reductase (protein R2) from E. coli, mouse, and herpes simplex virus (HSV-2) by a series of p-alkoxyphenols with different alkyl chains, have been studied by stopped-flow
I Islam et al.
Journal of medicinal chemistry, 34(10), 2954-2961 (1991-10-01)
Described herein are structure-activity studies of new antitumor agents based on the pyrrolo[1,2-a]benzimidazole (PBI) ring system. These compounds were designed as new DNA cross-linkers mimicking the mitomycin antitumor agents. Actually, the PBI derivatives were found to have anthracycline-like features: (i)
F J Hornicek et al.
Chemico-biological interactions, 55(3), 289-302 (1985-11-01)
Nitroxyldisulfonate [Fremy's salt; (KSO3)2NO.] and bisulfite (NaHSO3) have abolished periodic acid (H5IO6)-induced blastogenesis of human peripheral blood lymphocytes (HPBL), but only inhibited the blastogenic response of H5IO6-oxidized rat and mouse lymphocytes, as determined by the rates of nucleic acids synthesis
Potassium Nitrosodisulfonate
Parker K, et al.
e-EROS Encyclopedia of Reagents for Organic Synthesis (2001)

문서

Oxidation and reduction reactions are some of the most common transformations encountered in organic synthesis

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